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TRA T cell receptor alpha locus [ Homo sapiens (human) ]

Gene ID: 6955, updated on 13-May-2015
Official Symbol
TRAprovided by HGNC
Official Full Name
T cell receptor alpha locusprovided by HGNC
Primary source
HGNC:HGNC:12027
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IMD7; TCRA; TCRD; TRA@; TRAC
See TRA in MapViewer
Location:
14q11.2
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 14 NC_000014.9 (21621904..22552132)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (22090057..23021075)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene olfactory receptor, family 10, subfamily G, member 1 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2N pseudogene 1 Neighboring gene T cell receptor alpha variable 1-1 Neighboring gene ADP-ribosylation factor-like 6 interacting protein 1 pseudogene 1 Neighboring gene T cell receptor alpha variable 1-2 Neighboring gene olfactory receptor, family 10, subfamily G, member 2 Neighboring gene olfactory receptor, family 4, subfamily E, member 2 Neighboring gene olfactory receptor, family 4, subfamily E, member 1 (gene/pseudogene) Neighboring gene T cell receptor alpha variable 2 Neighboring gene T cell receptor alpha variable 3 (gene/pseudogene) Neighboring gene T cell receptor alpha variable 4 Neighboring gene ribosomal protein L4 pseudogene 1 Neighboring gene T cell receptor alpha variable 5 Neighboring gene T cell receptor alpha variable 8-1 Neighboring gene T cell receptor alpha variable 6 Neighboring gene T cell receptor alpha variable 7 Neighboring gene T cell receptor alpha variable 9-1 Neighboring gene T cell receptor alpha variable 12-1 Neighboring gene T cell receptor alpha variable 10 Neighboring gene T cell receptor alpha variable 11 (pseudogene) Neighboring gene T cell receptor alpha variable 8-2 Neighboring gene T cell receptor alpha variable 8-3 Neighboring gene T cell receptor alpha variable 13-1 Neighboring gene T cell receptor alpha variable 12-2 Neighboring gene T cell receptor alpha variable 8-4 Neighboring gene T cell receptor alpha variable 14/delta variable 4 Neighboring gene T cell receptor alpha variable 8-5 (pseudogene) Neighboring gene T cell receptor alpha variable 13-2 Neighboring gene T cell receptor alpha variable 9-2 Neighboring gene spalt-like transcription factor 4 pseudogene Neighboring gene T cell receptor alpha variable 12-3 Neighboring gene T cell receptor alpha variable 15 (pseudogene) Neighboring gene T cell receptor alpha variable 8-6 Neighboring gene T cell receptor alpha variable 16 Neighboring gene T cell receptor alpha variable 17 Neighboring gene T cell receptor alpha variable 18 Neighboring gene T cell receptor alpha variable 19 Neighboring gene T cell receptor alpha variable 20 Neighboring gene T cell receptor alpha variable 23/delta variable 6 Neighboring gene T cell receptor alpha variable 21 Neighboring gene T cell receptor alpha variable 22 Neighboring gene uncharacterized LOC105370403 Neighboring gene T cell receptor alpha variable 26-1 Neighboring gene T cell receptor alpha variable 24 Neighboring gene T cell receptor delta variable 1 Neighboring gene T cell receptor alpha variable 25 Neighboring gene T cell receptor alpha variable 8-7 (non-functional) Neighboring gene T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene) Neighboring gene T cell receptor alpha variable 27 Neighboring gene T cell receptor alpha variable 28 (pseudogene) Neighboring gene T cell receptor alpha variable 30 Neighboring gene T cell receptor alpha variable 26-2 Neighboring gene T cell receptor alpha variable 31 (pseudogene) Neighboring gene T cell receptor alpha variable 36/delta variable 7 Neighboring gene T cell receptor alpha variable 32 (pseudogene) Neighboring gene T cell receptor alpha variable 33 (pseudogene) Neighboring gene T cell receptor alpha variable 34 Neighboring gene T cell receptor alpha variable 38-2/delta variable 8 Neighboring gene T cell receptor alpha variable 35 Neighboring gene T cell receptor alpha variable 38-1 Neighboring gene translin-associated factor X pseudogene Neighboring gene T cell receptor alpha variable 37 (pseudogene) Neighboring gene uncharacterized LOC105370402 Neighboring gene T cell receptor alpha variable 39 Neighboring gene T cell receptor alpha variable 40 Neighboring gene T cell receptor alpha variable 41 Neighboring gene uncharacterized LOC105370401 Neighboring gene T cell receptor delta variable 2 Neighboring gene T cell receptor delta diversity 1 Neighboring gene T cell receptor delta diversity 2 Neighboring gene T cell receptor delta joining 1 Neighboring gene T cell receptor delta locus Neighboring gene T cell receptor delta diversity 3 Neighboring gene T cell receptor delta joining 4 Neighboring gene T cell receptor delta joining 2 Neighboring gene T cell receptor delta joining 3 Neighboring gene uncharacterized LOC105370400 Neighboring gene uncharacterized LOC105370399 Neighboring gene T cell receptor alpha joining 58 (non-functional) Neighboring gene T cell receptor alpha joining 59 (non-functional) Neighboring gene T cell receptor alpha joining 60 (pseudogene) Neighboring gene T cell receptor alpha joining 61 (non-functional) Neighboring gene T cell receptor alpha joining 57 Neighboring gene T cell receptor alpha joining 56 Neighboring gene T cell receptor alpha joining 55 (pseudogene) Neighboring gene T cell receptor alpha joining 54 Neighboring gene T cell receptor alpha joining 53 Neighboring gene T cell receptor delta variable 3 Neighboring gene T cell receptor alpha joining 52 Neighboring gene T cell receptor alpha joining 51 (pseudogene) Neighboring gene T cell receptor alpha joining 50 Neighboring gene T cell receptor alpha joining 49 Neighboring gene T cell receptor delta constant Neighboring gene T cell receptor alpha joining 48 Neighboring gene T cell receptor alpha joining 47 Neighboring gene T cell receptor alpha joining 45 Neighboring gene T cell receptor alpha joining 46 Neighboring gene T cell receptor alpha joining 44 Neighboring gene T cell receptor alpha joining 43 Neighboring gene T cell receptor alpha joining 42 Neighboring gene T cell receptor alpha joining 41 Neighboring gene T cell receptor alpha joining 40 Neighboring gene T cell receptor alpha joining 39 Neighboring gene T cell receptor alpha joining 38 Neighboring gene T cell receptor alpha joining 37 Neighboring gene T cell receptor alpha joining 36 Neighboring gene T cell receptor alpha joining 35 (non-functional) Neighboring gene T cell receptor alpha joining 34 Neighboring gene T cell receptor alpha joining 32 Neighboring gene T cell receptor alpha joining 33 Neighboring gene T cell receptor alpha joining 31 Neighboring gene T cell receptor alpha joining 30 Neighboring gene T cell receptor alpha joining 29 Neighboring gene T cell receptor alpha joining 28 Neighboring gene T cell receptor alpha joining 27 Neighboring gene T cell receptor alpha joining 26 Neighboring gene T cell receptor alpha joining 25 (non-functional) Neighboring gene T cell receptor alpha joining 24 Neighboring gene T cell receptor alpha joining 23 Neighboring gene T cell receptor alpha joining 21 Neighboring gene T cell receptor alpha joining 20 Neighboring gene T cell receptor alpha joining 22 Neighboring gene T cell receptor alpha joining 19 (non-functional) Neighboring gene T cell receptor alpha joining 18 Neighboring gene T cell receptor alpha joining 17 Neighboring gene T cell receptor alpha joining 16 Neighboring gene T cell receptor alpha joining 15 Neighboring gene T cell receptor alpha joining 13 Neighboring gene T cell receptor alpha joining 11 Neighboring gene T cell receptor alpha joining 12 Neighboring gene T cell receptor alpha joining 14 Neighboring gene T cell receptor alpha joining 10 Neighboring gene T cell receptor alpha joining 9 Neighboring gene T cell receptor alpha joining 8 Neighboring gene T cell receptor alpha joining 7 Neighboring gene T cell receptor alpha joining 6 Neighboring gene T cell receptor alpha joining 5 Neighboring gene T cell receptor alpha joining 4 Neighboring gene T cell receptor alpha joining 3 Neighboring gene T cell receptor alpha joining 2 (non-functional) Neighboring gene T cell receptor alpha joining 1 (non-functional) Neighboring gene T cell receptor alpha constant Neighboring gene defender against cell death 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
A genome-wide association study of recipient genotype and medium-term kidney allograft function.
NHGRI GWA Catalog
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
NHGRI GWA Catalog
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
NHGRI GWA Catalog
Genome-wide association study and meta-analysis of intraocular pressure.
NHGRI GWA Catalog
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
NHGRI GWA Catalog
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
NHGRI GWA Catalog
Narcolepsy is strongly associated with the T-cell receptor alpha locus.
NHGRI GWA Catalog
  • Cytokines and Inflammatory Response, organism-specific biosystem (from WikiPathways)
    Cytokines and Inflammatory Response, organism-specific biosystemInflammation is a protective response to infection by the immune system that requires communication between different classes of immune cells to coordinate their actions. Acute inflammation is an imp...
  • TCR Signaling Pathway, organism-specific biosystem (from WikiPathways)
    TCR Signaling Pathway, organism-specific biosystemThe T-cell antigen receptor (TCR) complex is composed of a ligand-binding subunit, the ? and ? chains, and a signaling subunit, namely the CD3?, ? and ? chains and the TCR? chain. This complex partic...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Other Names

  • T-cell antigen receptor, alpha polypeptide
  • T-cell receptor, alpha (V,D,J,C)

Clone Names

  • FLJ22602, MGC22624, MGC23964, MGC71411, MGC117436
Names
T cell receptor alpha locus
T-cell antigen receptor, alpha polypeptide
T-cell receptor, alpha (V,D,J,C)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_001332.2 

    Range
    145152..1076166
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p2 Primary Assembly

    Range
    21621904..22552132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018925.2 Alternate CHM1_1.1

    Range
    22089806..23020034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)