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Polr2b polymerase (RNA) II (DNA directed) polypeptide B [ Mus musculus (house mouse) ]

Gene ID: 231329, updated on 26-Aug-2014
Official Symbol
Polr2bprovided by MGI
Official Full Name
polymerase (RNA) II (DNA directed) polypeptide Bprovided by MGI
Primary source
MGI:2388280
See related
Ensembl:ENSMUSG00000029250; Vega:OTTMUSG00000026994
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpb2; Pol2rb; Rpb140
See Polr2b in Epigenomics, MapViewer
Location:
5 C3.3; 5
Exon count:
25
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (77310484..77349328)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene RE1-silencing transcription factor Neighboring gene microRNA 5098 Neighboring gene nitric oxide associated 1 Neighboring gene insulin-like growth factor binding protein 7 Neighboring gene uncharacterized LOC102637968 Neighboring gene uncharacterized LOC102638079

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC47046

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-directed RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase II activity IBA
Inferred from Biological aspect of Ancestor
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
ribonucleoside binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
DNA-directed RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
 
DNA-directed RNA polymerase II, core complex ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus IC
Inferred by Curator
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
DNA-directed RNA polymerase II subunit RPB2
Names
DNA-directed RNA polymerase II subunit RPB2
RNA polymerase II subunit 2
RNA polymerase II subunit B2
DNA-directed RNA polymerase II subunit B
DNA-directed RNA polymerase II 140 kDa polypeptide
NP_722493.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153798.2NP_722493.2  DNA-directed RNA polymerase II subunit RPB2

    See proteins identical to NP_722493.2

    Status: VALIDATED

    Source sequence(s)
    AA501042, AK039766, BQ177004, CF155991, CF553167, CN690754
    Consensus CDS
    CCDS51528.1
    UniProtKB/Swiss-Prot
    Q8CFI7
    Related
    ENSMUSP00000031167, OTTMUSP00000033478, ENSMUST00000031167, OTTMUST00000066713
    Conserved Domains (4) summary
    pfam04566
    Location:567629
    Blast Score: 299
    RNA_pol_Rpb2_4; RNA polymerase Rpb2, domain 4
    pfam04567
    Location:653700
    Blast Score: 195
    RNA_pol_Rpb2_5; RNA polymerase Rpb2, domain 5
    PRK08565
    Location:271172
    Blast Score: 3324
    PRK08565; DNA-directed RNA polymerase subunit B; Provisional
    cd00653
    Location:391172
    Blast Score: 3245
    RNA_pol_B_RPB2; RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    77310484..77349328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    74577709..74617045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)