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Cyb5r3 cytochrome b5 reductase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25035, updated on 24-Jan-2015
Official Symbol
Cyb5r3provided by RGD
Official Full Name
cytochrome b5 reductase 3provided by RGD
Primary source
RGD:2502
See related
Ensembl:ENSRNOG00000009592
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Dia1; Nadhcb5; RNNADHCB5
Summary
catalyzes the conversion of NADH, H+, and 2 ferricytochrome b(5) to NAD+ and 2 ferrocytochrome b(5) [RGD, Feb 2006]
Orthologs
See Cyb5r3 in MapViewer
Location:
7q34
Exon count:
10
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (124024003..124041564, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (124006942..124024503, complement)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene serine hydrolase-like 2 Neighboring gene ribosomal RNA processing 7 homolog A (S. cerevisiae) Neighboring gene polymerase (DNA-directed), delta interacting protein 3 Neighboring gene alpha 1,4-galactosyltransferase Neighboring gene similar to 60S ribosomal protein L36

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ADP binding IDA
Inferred from Direct Assay
more info
PubMed 
AMP binding IDA
Inferred from Direct Assay
more info
PubMed 
FAD binding IEA
Inferred from Electronic Annotation
more info
 
FAD binding ISO
Inferred from Sequence Orthology
more info
 
NAD binding IDA
Inferred from Direct Assay
more info
PubMed 
cytochrome-b5 reductase activity, acting on NAD(P)H TAS
Traceable Author Statement
more info
PubMed 
flavin adenine dinucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular vesicular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
lipid particle IEA
Inferred from Electronic Annotation
more info
 
lipid particle ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
NADH-cytochrome b5 reductase 3
Names
NADH-cytochrome b5 reductase 3
B5R
diaphorase 1
diaphorase-1
Diaphorase (NADH) (cytochrome b-5 reductase)
NP_620232.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138877.1NP_620232.1  NADH-cytochrome b5 reductase 3

    See proteins identical to NP_620232.1

    Status: PROVISIONAL

    Source sequence(s)
    D00636
    UniProtKB/Swiss-Prot
    P20070
    Conserved Domains (2) summary
    cd06183
    Location:45301
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
    PTZ00319
    Location:16301
    PTZ00319; NADH-cytochrome B5 reductase; Provisional

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 

    Range
    124024003..124041564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242065.2XP_006242127.1  

    UniProtKB/Swiss-Prot
    P20070
    Related
    ENSRNOP00000012878
    Conserved Domains (2) summary
    cd06183
    Location:51307
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
    PTZ00319
    Location:22307
    PTZ00319; NADH-cytochrome B5 reductase; Provisional

Alternate Rn_Celera

Genomic

  1. AC_000075.1 

    Range
    110620903..110638468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)