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    LOC100012472 interstitial collagenase [ Monodelphis domestica (gray short-tailed opossum) ]

    Gene ID: 100012472, updated on 2-Nov-2023

    Summary

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    Gene symbol
    LOC100012472
    Gene description
    interstitial collagenase
    See related
    Ensembl:ENSMODG00000000712
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Monodelphis domestica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
    Also known as
    MMP1
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    Genomic context

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    See LOC100012472 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 4 NC_077230.1 (253819926..253831799)
    103 previous assembly MonDom5 (GCF_000002295.2) 4 NC_008804.1 (259344625..259356650, complement)

    Chromosome 4 - NC_077230.1Genomic Context describing neighboring genes Neighboring gene macrophage metalloelastase Neighboring gene stromelysin-1 Neighboring gene neutrophil collagenase Neighboring gene matrix metallopeptidase 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interstitial collagenase
    Names
    matrix metallopeptidase 1 (interstitial collagenase)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMonDom1.pri

    Genomic

    1. NC_077230.1 Reference mMonDom1.pri

      Range
      253819926..253831799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001366747.5 → XP_001366784.1  interstitial collagenase

      UniProtKB/TrEMBL
      F6WL75
      Related
      ENSMODP00000000855.3
      Conserved Domains (4) summary
      cd00094
      Location:275 → 466
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:106 → 261
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam00413
      Location:106 → 261
      Peptidase_M10; Matrixin
      pfam01471
      Location:27 → 85
      PG_binding_1; Putative peptidoglycan binding domain
    Nucleotide Protein
    Heading Accession and Version

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