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    AT1G59910 Actin-binding FH2 (formin homology 2) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842285, updated on 15-Feb-2024

    Summary

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    Gene symbol
    AT1G59910
    Gene description
    Actin-binding FH2 (formin homology 2) family protein
    Primary source
    Araport:AT1G59910
    Locus tag
    AT1G59910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F23H11.22; F23H11_22
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (22053863..22057268, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene SIN3-like 5 Neighboring gene pyruvate dehydrogenase complex E1 alpha subunit Neighboring gene MADS-box family protein Neighboring gene MADS-box family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Formin homology 2 domains occur in multiple contexts in angiosperms. Cvrcková F, et al. BMC Genomics, 2004 Jul 15. PMID 15256004, Free PMC Article
    2. Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. Deeks MJ, et al. Trends Plant Sci, 2002 Nov. PMID 12417149
    3. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    4. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_104683.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin nucleation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Actin-binding FH2 (formin homology 2) family protein
    NP_176199.1
    • Actin-binding FH2 (formin homology 2) family protein; FUNCTIONS IN: actin binding; INVOLVED IN: cellular component organization, actin cytoskeleton organization; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: formin 8 (TAIR:AT1G70140.1); Has 156785 Blast hits to 84417 proteins in 2586 species: Archae - 222; Bacteria - 29191; Metazoa - 66130; Fungi - 20882; Plants - 16945; Viruses - 3579; Other Eukaryotes - 19836 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22053863..22057268 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104683.3 → NP_176199.1  Actin-binding FH2 (formin homology 2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176199.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XIE0
      UniProtKB/TrEMBL
      A0A178WAN0, A0A654EL31
      Conserved Domains (2) summary
      PHA03247
      Location:242 → 363
      PHA03247; large tegument protein UL36; Provisional
      pfam02181
      Location:453 → 859
      FH2; Formin Homology 2 Domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XIE0.1

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