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    wecE dTDP-4-dehydro-6-deoxy-D-glucose transaminase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948296, updated on 23-Nov-2023

    Summary

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    Gene symbol
    wecE
    Gene description
    dTDP-4-dehydro-6-deoxy-D-glucose transaminase
    Primary source
    ASAP:ABE-0012384
    Locus tag
    b3791
    See related
    ECOCYC:EG11456
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3783; fcnA; rff; rffA; yifI
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    Genomic context

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    Sequence:
    NC_000913.3 (3975146..3976276)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-N-acetyl-D-mannosamine dehydrogenase Neighboring gene dTDP-glucose 4,6-dehydratase 2 Neighboring gene glucose-1-phosphate thymidylyltransferase 2 Neighboring gene RffC Neighboring gene lipid IIIECA flippase Neighboring gene TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase Neighboring gene enterobacterial common antigen polymerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12. Hwang BY, et al. Chem Biol, 2004 Jul. PMID 15271350
    2. Physical map location of the rffC and rffA genes of Escherichia coli. Barr K, et al. J Bacteriol, 1993 Sep. PMID 8366065, Free PMC Article
    3. Toxicity-based selection of Escherichia coli mutants for functional recombinant protein production: application to an antibody fragment. Belin P, et al. Protein Eng Des Sel, 2004 May. PMID 15252207
    4. Accumulation of the enterobacterial common antigen lipid II biosynthetic intermediate stimulates degP transcription in Escherichia coli. Danese PN, et al. J Bacteriol, 1998 Nov. PMID 9811644, Free PMC Article
    5. Nucleotide sequence of the Escherichia coli rfe gene involved in the synthesis of enterobacterial common antigen. Molecular cloning of the rfe-rff gene cluster. Meier-Dieter U, et al. J Biol Chem, 1992 Jan 15. PMID 1730666

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dTDP-4-amino-4,6-dideoxygalactose transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dTDP-4-amino-4,6-dideoxygalactose transaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dTDP-4-amino-4,6-dideoxygalactose transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in enterobacterial common antigen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within enterobacterial common antigen biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in polysaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    dTDP-4-dehydro-6-deoxy-D-glucose transaminase
    NP_418238.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3975146..3976276
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418238.1 dTDP-4-dehydro-6-deoxy-D-glucose transaminase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418238.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A826TWV1, F4V8B3
      Conserved Domains (1) summary
      PRK11706
      Location:1 → 376
      PRK11706; TDP-4-oxo-6-deoxy-D-glucose transaminase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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