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    sufB Fe-S cluster scaffold complex subunit SufB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945753, updated on 4-Apr-2024

    Summary

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    Gene symbol
    sufB
    Gene description
    Fe-S cluster scaffold complex subunit SufB
    Primary source
    ASAP:ABE-0005621
    Locus tag
    b1683
    See related
    ECOCYC:G6909
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1679; ynhE
    Summary
    SufBCD increases SufSE cysteine desulfurase activity and involved in iron acquisition. [More information is available at EcoGene: EG13965]. The SufB-SufC-SufD complex activates the cysteine desulfurase activity SufS in conjunction with the SufE sulfur acceptor protein . [More information is available at EcoCyc: G6909].
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    Genomic context

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    Sequence:
    NC_000913.3 (1762522..1764009, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-cysteine desulfurase Neighboring gene Fe-S cluster scaffold complex subunit SufD Neighboring gene Fe-S cluster scaffold complex subunit SufC Neighboring gene iron-sulfur cluster insertion protein SufA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular investigation of iron-sulfur cluster assembly scaffolds under stress. Blanc B, et al. Biochemistry, 2014 Dec 23. PMID 25485887
    2. SufC hydrolyzes ATP and interacts with SufB from Thermotoga maritima. Rangachari K, et al. FEBS Lett, 2002 Mar 13. PMID 11943156
    3. Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor. Wollers S, et al. J Biol Chem, 2010 Jul 23. PMID 20460376, Free PMC Article
    4. Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex. Wada K, et al. J Mol Biol, 2009 Mar 20. PMID 19361433, Free PMC Article
    5. AtNAP1 represents an atypical SufB protein in Arabidopsis plastids. Xu XM, et al. J Biol Chem, 2005 Feb 25. PMID 15611066, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 4 iron, 4 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within iron-sulfur cluster assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of iron-sulfur cluster assembly complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of iron-sulfur cluster assembly complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Fe-S cluster scaffold complex subunit SufB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1762522..1764009 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416198.2 Fe-S cluster scaffold complex subunit SufB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416198.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A828ABU4
      Conserved Domains (1) summary
      PRK11814
      Location:1 → 495
      PRK11814; cysteine desulfurase activator complex subunit SufB; Provisional
    Nucleotide Protein
    Heading Accession and Version

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