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    CBP2 Cbp2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856347, updated on 13-Apr-2024

    Summary

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    Gene symbol
    CBP2
    Gene description
    Cbp2p
    Primary source
    SGD:S000001030
    Locus tag
    YHL038C
    See related
    AllianceGenome:SGD:S000001030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA binding activity. Involved in Group I intron splicing and mitochondrial mRNA processing. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (23617..25509, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene siderophore transporter Neighboring gene protein-lysine N-methyltransferase Neighboring gene uncharacterized protein Neighboring gene Mup3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A glucose-starvation response regulates the diffusion of macromolecules. Joyner RP, et al. Elife, 2016 Mar 22. PMID 27003290, Free PMC Article
    2. A collapsed state functions to self-chaperone RNA folding into a native ribonucleoprotein complex. Webb AE, et al. Nat Struct Biol, 2001 Feb. PMID 11175902
    3. An RNA binding motif in the Cbp2 protein required for protein-stimulated RNA catalysis. Tirupati HK, et al. J Biol Chem, 1999 Oct 22. PMID 10521416
    4. The novel function of the Saccharomyces cerevisiae CBP2 gene as a splicing factor essential to excision of the Saccharomyces douglasii LSU intron in vivo. Tian GL, et al. Mol Gen Genet, 1998 Apr. PMID 9613573
    5. The Cbp2 protein stimulates the splicing of the omega intron of yeast mitochondria. Shaw LC, et al. Nucleic Acids Res, 1997 Apr 15. PMID 9092668, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Group I intron splicing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in Group I intron splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cbp2p
    NP_011825.1
    • Required for splicing of the group I intron bI5 of the COB pre-mRNA; nuclear-encoded mitochondrial protein that binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      23617..25509 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179118.1 → NP_011825.1  TPA: Cbp2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011825.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKT1, P03874
      UniProtKB/TrEMBL
      A0A8H4F9S3, A6ZSL3, C7GRT5, C8ZA25, N1P370
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P03874.2

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