adal adenosine deaminase-like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: adalprovided by ZNC
Official Full Name: adenosine deaminase-likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050913-145
See related: Ensembl:ENSDARG00000012986 AllianceGenome:ZFIN:ZDB-GENE-050913-145
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:109912
Summary: Predicted to enable adenosine deaminase activity. Acts upstream of or within camera-type eye development. Is expressed in several structures, including gill; heart; kidney; liver; and muscle. Orthologous to human ADAL (adenosine deaminase like). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (20567804..20574811, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (20470150..20477157, complement)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables N6-methyl-AMP deaminase activity	IEA Inferred from Electronic Annotation more info
enables adenosine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in adenosine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within camera-type eye development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in inosine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within nucleotide metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: adenosine deaminase-like protein

NP_001028916.1

EC 3.5.4.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033744.1 → NP_001028916.1 adenosine deaminase-like protein

See identical proteins and their annotated locations for NP_001028916.1

Status: PROVISIONAL

Source sequence(s)

BC096787

UniProtKB/Swiss-Prot

A7MCN2, Q4V9P6

Related

ENSDARP00000067287.6, ENSDART00000067288.7

Conserved Domains (1) summary

cd00443
Location:12 → 339

ADA_AMPD; Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase ...