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    Zfp979 zinc finger protein 979 [ Mus musculus (house mouse) ]

    Gene ID: 112422, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp979provided by MGI
    Official Full Name
    zinc finger protein 979provided by MGI
    Primary source
    MGI:MGI:2148252
    See related
    Ensembl:ENSMUSG00000066000 AllianceGenome:MGI:2148252
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ssm1b; 2610305D13Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus and ovary. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in liver E14 (RPKM 1.1), bladder adult (RPKM 0.9) and 17 other tissues See more
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    Genomic context

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    Location:
    4; 4 E1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147696393..147727004, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147611936..147642508, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr4:146902715-146903015 Neighboring gene 60S ribosomal protein L29 pseudogene Neighboring gene STARR-seq mESC enhancer starr_12057 Neighboring gene STARR-seq mESC enhancer starr_12058 Neighboring gene zinc finger protein 985 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146958877-146959178 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146960015-146960316 Neighboring gene high mobility group box 1-like pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr4:147051587-147051888 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147058330-147058631 Neighboring gene zinc finger protein 534 Neighboring gene STARR-seq mESC enhancer starr_12059 Neighboring gene STARR-positive B cell enhancer mm9_chr4:147083962-147084263 Neighboring gene STARR-seq mESC enhancer starr_12060 Neighboring gene predicted gene 13137

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Ssm1b expression and function in germ cells of adult mice and in early embryos. Ratnam S, et al. Mol Reprod Dev, 2017 Jul. PMID 28464323
    2. Identification of Ssm1b, a novel modifier of DNA methylation, and its expression during mouse embryogenesis. Ratnam S, et al. Development, 2014 May. PMID 24803651, Free PMC Article
    3. Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. Dietrich JE, et al. EMBO Rep, 2015 Aug. PMID 26142281, Free PMC Article
    4. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
    5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC112422

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145078.2 → NP_659544.2  uncharacterized protein LOC112422

      Status: VALIDATED

      Source sequence(s)
      AL606910, CD548052, CF161903, DV659285
      Consensus CDS
      CCDS59663.1
      UniProtKB/TrEMBL
      A2A799
      Related
      ENSMUSP00000038153.8, ENSMUST00000037565.14
      Conserved Domains (5) summary
      smart00349
      Location:28 → 70
      KRAB; krueppel associated box
      COG5048
      Location:82 → 407
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:259 → 279
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:28 → 67
      KRAB; KRAB box
      pfam13465
      Location:355 → 380
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      147696393..147727004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319919.2 → XP_017175408.1  uncharacterized protein LOC112422 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:29 → 346
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:256 → 339
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:206 → 226
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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