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    TERT telomerase reverse transcriptase [ Equus caballus (horse) ]

    Gene ID: 100630695, updated on 8-Mar-2024

    Summary

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    Gene symbol
    TERT
    Gene description
    telomerase reverse transcriptase
    See related
    Ensembl:ENSECAG00000001347
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 21
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (58026104..58049702)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 21 NC_009164.2 (56779552..56803329)

    Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106782354 Neighboring gene CLPTM1 like Neighboring gene microRNA mir-8960 Neighboring gene solute carrier family 6 member 18 Neighboring gene solute carrier family 6 member 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables telomerase RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomerase RNA reverse transcriptase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in telomere maintenance via telomerase IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of telomerase catalytic core complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    telomerase reverse transcriptase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009164.3 Reference EquCab3.0 Primary Assembly

      Range
      58026104..58049702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023625881.1 → XP_023481649.1  telomerase reverse transcriptase isoform X1

      UniProtKB/TrEMBL
      F6VCD9
      Related
      ENSECAP00000001280.2, ENSECAT00000001711.3
      Conserved Domains (4) summary
      cd01648
      Location:839 → 955
      TERT; Telomerase reverse transcriptase (TERT). Telomerase is a ribonucleoprotein (RNP) that synthesizes telomeric DNA repeats. The telomerase RNA subunit provides the template for synthesis of these repeats. The catalytic subunit of RNP is known as telomerase ...
      pfam12009
      Location:474 → 599
      Telomerase_RBD; Telomerase ribonucleoprotein complex - RNA binding domain
      cl27975
      Location:240 → 468
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28033
      Location:173 → 332
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    2. XM_023625882.1 → XP_023481650.1  telomerase reverse transcriptase isoform X2

      UniProtKB/TrEMBL
      A0A3Q2HXK7
      Related
      ENSECAP00000038106.2, ENSECAT00000058352.2
      Conserved Domains (4) summary
      cd01648
      Location:839 → 950
      TERT; Telomerase reverse transcriptase (TERT). Telomerase is a ribonucleoprotein (RNP) that synthesizes telomeric DNA repeats. The telomerase RNA subunit provides the template for synthesis of these repeats. The catalytic subunit of RNP is known as telomerase ...
      pfam12009
      Location:474 → 599
      Telomerase_RBD; Telomerase ribonucleoprotein complex - RNA binding domain
      cl27975
      Location:240 → 468
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28033
      Location:173 → 332
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    3. XM_023625883.1 → XP_023481651.1  telomerase reverse transcriptase isoform X3

      UniProtKB/TrEMBL
      A0A3Q2H3P6
      Related
      ENSECAP00000028240.2, ENSECAT00000045165.2
      Conserved Domains (4) summary
      cd01648
      Location:839 → 926
      TERT; Telomerase reverse transcriptase (TERT). Telomerase is a ribonucleoprotein (RNP) that synthesizes telomeric DNA repeats. The telomerase RNA subunit provides the template for synthesis of these repeats. The catalytic subunit of RNP is known as telomerase ...
      pfam12009
      Location:474 → 599
      Telomerase_RBD; Telomerase ribonucleoprotein complex - RNA binding domain
      cl27975
      Location:240 → 468
      EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
      cl28033
      Location:173 → 332
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    RNA

    1. XR_002802683.1 RNA Sequence

    2. XR_002802682.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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