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    KAT2B lysine acetyltransferase 2B [ Equus caballus (horse) ]

    Gene ID: 100061976, updated on 8-Mar-2024

    Summary

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    Official Symbol
    KAT2Bprovided by VGNC
    Official Full Name
    lysine acetyltransferase 2Bprovided by VGNC
    Primary source
    VGNC:VGNC:19242
    See related
    Ensembl:ENSECAG00000013925
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    PCAF
    Orthologs
    human mouse all
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    Genomic context

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    See KAT2B in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 16 NC_009159.3 (63630857..63724884, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 16 NC_009159.2 (62046995..62137092, complement)

    Chromosome 16 - NC_009159.3Genomic Context describing neighboring genes Neighboring gene transcription initiation factor TFIID subunit 6 pseudogene Neighboring gene shugoshin 1 Neighboring gene protein phosphatase 2C like domain containing 1 Neighboring gene RAB5A, member RAS oncogene family Neighboring gene small nucleolar RNA SNORA57 Neighboring gene EF-hand domain family member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3 acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of histone acetyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone acetyltransferase KAT2B
    Names
    p300/CBP-associated factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009159.3 Reference EquCab3.0 Primary Assembly

      Range
      63630857..63724884 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023620862.1 → XP_023476630.1  histone acetyltransferase KAT2B isoform X1

      UniProtKB/TrEMBL
      A0A3Q2I8L6, A0A3Q2L420
      Related
      ENSECAP00000032738.1, ENSECAT00000062387.2
      Conserved Domains (3) summary
      cd05509
      Location:719 → 818
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      pfam00583
      Location:514 → 614
      Acetyltransf_1; Acetyltransferase (GNAT) family
      pfam06466
      Location:66 → 317
      PCAF_N; PCAF (P300/CBP-associated factor) N-terminal domain

    2. XM_014731840.2 → XP_014587326.1  histone acetyltransferase KAT2B isoform X3

      UniProtKB/TrEMBL
      F7D5G4
      Conserved Domains (4) summary
      cd05509
      Location:570 → 669
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5076
      Location:330 → 669
      COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
      pfam00583
      Location:393 → 465
      Acetyltransf_1; Acetyltransferase (GNAT) family
      pfam06466
      Location:1 → 168
      PCAF_N; PCAF (P300/CBP-associated factor) N-terminal domain

    3. XM_023620863.1 → XP_023476631.1  histone acetyltransferase KAT2B isoform X2

      UniProtKB/TrEMBL
      A0A3Q2I8L6
      Related
      ENSECAP00000043749.2, ENSECAT00000045420.2
      Conserved Domains (2) summary
      pfam06466
      Location:66 → 317
      PCAF_N; PCAF (P300/CBP-associated factor) N-terminal domain
      cl02556
      Location:479 → 644
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    RNA

    1. XR_002800754.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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