These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001256702.1 → NP_001243631.1 ubiquitin carboxyl-terminal hydrolase 3 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AC118274, AK301236, BC065300, DA557812
- UniProtKB/TrEMBL
-
B4DVU5
- UniProtKB/TrEMBL
-
F5H1A6
- UniProtKB/Swiss-Prot
-
Q9Y6I4
- Conserved Domains (3) summary
-
- cl02553
Location:116 – 465
Blast Score: 485
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:114 – 464
Blast Score: 490
- UCH; Ubiquitin carboxyl-terminal hydrolase
- cl09957
Location:29 – 53
Blast Score: 85
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
-
NM_006537.3 → NP_006528.2 ubiquitin carboxyl-terminal hydrolase 3 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AC118274, AK314223, DA557812
- Consensus CDS
-
CCDS32265.1
- UniProtKB/Swiss-Prot
-
Q9Y6I4
- Related
- ENSP00000369681, OTTHUMP00000248079, ENST00000380324, OTTHUMT00000417773
- Conserved Domains (3) summary
-
- cl02553
Location:160 – 509
Blast Score: 480
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:158 – 508
Blast Score: 487
- UCH; Ubiquitin carboxyl-terminal hydrolase
- cl09957
Location:29 – 105
Blast Score: 178
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
RNA
-
NR_046341.1 RNA Sequence
- Description
- Transcript Variant: This variant (3) includes an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC118274, AY461579, DA557812
-
NR_046342.1 RNA Sequence
- Description
- Transcript Variant: This variant (4) includes an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC118274, BC065300, BX647760, DA557812
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000015.9 Reference GRCh37.p5 Primary Assembly
- Range
- 63796810..63883663
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000147.1 Alternate HuRef
- Range
- 40621387..40708094
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)