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UBAP2L ubiquitin associated protein 2 like [ Homo sapiens (human) ]

Gene ID: 9898, updated on 8-May-2016
Official Symbol
UBAP2Lprovided by HGNC
Official Full Name
ubiquitin associated protein 2 likeprovided by HGNC
Primary source
HGNC:HGNC:29877
See related
Ensembl:ENSG00000143569 HPRD:06665; MIM:616472; Vega:OTTHUMG00000035983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NICE4; NICE-4
Orthologs
Location:
1q21.3
Exon count:
33
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (154219951..154271510)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (154192427..154243986)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene microRNA 190b Neighboring gene chromosome 1 open reading frame 189 Neighboring gene chromosome 1 open reading frame 43 Neighboring gene HCLS1 associated protein X-1 Neighboring gene aquaporin 10

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag Cellular biotinylated ubiquitin associated protein 2-like (UBAP2L) is incorporated into HIV-1 Gag virus-like particles PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ42300, KIAA0144

Gene Ontology Provided by GOA

Function Evidence Code Pubs
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
binding of sperm to zona pellucida IMP
Inferred from Mutant Phenotype
more info
PubMed 
hematopoietic stem cell homeostasis IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with Ada2/Gcn5/Ada3 transcription activator complex IDA
Inferred from Direct Assay
more info
PubMed 
PcG protein complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
ubiquitin-associated protein 2-like
Names
protein NICE-4
ubiquitin associated protein 2-like

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127320.2NP_001120792.1  ubiquitin-associated protein 2-like isoform b

    See identical proteins and their annotated locations for NP_001120792.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the UTRs and 3' coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    D63478, DC369803
    Consensus CDS
    CCDS44229.1
    UniProtKB/Swiss-Prot
    Q14157
    Related
    ENSP00000345308, OTTHUMP00000034205, ENST00000343815, OTTHUMT00000087674
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  2. NM_001287815.1NP_001274744.1  ubiquitin-associated protein 2-like isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the UTRs, uses an alternate in-frame splice site in the central coding region, and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (c) is shorter and has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AK303533, D63478, DC404293
    Consensus CDS
    CCDS72925.1
    UniProtKB/Swiss-Prot
    Q14157
    Related
    ENSP00000478447, ENST00000613315
    Conserved Domains (2) summary
    pfam12478
    Location:487519
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  3. NM_001287816.1NP_001274745.1  ubiquitin-associated protein 2-like isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate in-frame splice site in the central coding region, and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (d) is shorter and has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AJ243670, AK302662, D63478, DC404293
    UniProtKB/Swiss-Prot
    Q14157
    UniProtKB/TrEMBL
    B4DYY5
    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  4. NM_014847.3NP_055662.3  ubiquitin-associated protein 2-like isoform a

    See identical proteins and their annotated locations for NP_055662.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    BC003170, D63478, DC404293
    Consensus CDS
    CCDS1063.1
    UniProtKB/Swiss-Prot
    Q14157
    Related
    ENSP00000389445, ENST00000428931
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    154219951..154271510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510214.1XP_011508516.1  

    See identical proteins and their annotated locations for XP_011508516.1

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  2. XM_011510217.1XP_011508519.1  

    See identical proteins and their annotated locations for XP_011508519.1

    UniProtKB/Swiss-Prot
    Q14157
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  3. XM_005245668.2XP_005245725.1  

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  4. XM_005245670.2XP_005245727.1  

    UniProtKB/TrEMBL
    F8W726
    Related
    ENSP00000271877, ENST00000271877
    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  5. XM_005245669.2XP_005245726.1  

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  6. XM_011510212.1XP_011508514.1  

    See identical proteins and their annotated locations for XP_011508514.1

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  7. XM_005245658.2XP_005245715.1  

    See identical proteins and their annotated locations for XP_005245715.1

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  8. XM_005245667.2XP_005245724.1  

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  9. XM_011510215.1XP_011508517.1  

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  10. XM_005245673.2XP_005245730.1  

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  11. XM_006711689.2XP_006711752.1  

    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  12. XM_005245672.2XP_005245729.1  

    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  13. XM_011510216.1XP_011508518.1  

    See identical proteins and their annotated locations for XP_011508518.1

    UniProtKB/Swiss-Prot
    Q14157
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  14. XM_005245674.1XP_005245731.1  

    See identical proteins and their annotated locations for XP_005245731.1

    UniProtKB/Swiss-Prot
    Q14157
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  15. XM_006711684.2XP_006711747.2  

    See identical proteins and their annotated locations for XP_006711747.2

    UniProtKB/Swiss-Prot
    Q14157
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  16. XM_011510213.1XP_011508515.1  

    See identical proteins and their annotated locations for XP_011508515.1

    Conserved Domains (2) summary
    pfam12478
    Location:505537
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  17. XM_006711685.2XP_006711748.2  

    See identical proteins and their annotated locations for XP_006711748.2

    UniProtKB/Swiss-Prot
    Q14157
    Conserved Domains (2) summary
    pfam12478
    Location:494526
    DUF3697; Ubiquitin-associated protein 2
    cd14277
    Location:5087
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
  18. XM_011510218.1XP_011508520.1  

    Conserved Domains (1) summary
    pfam12478
    Location:299331
    DUF3697; Ubiquitin-associated protein 2
  19. XM_006711687.2XP_006711750.2  

    Conserved Domains (1) summary
    pfam12478
    Location:264296
    DUF3697; Ubiquitin-associated protein 2

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    155588957..155640319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)