URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) [Homo sapiens] - Gene

Help top of page

Summary

Official Symbol: URB1provided by HGNC
Official Full Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)provided by HGNC
Primary source: HGNC:17344
See related: Ensembl:ENSG00000142207; MIM:608865; Vega:OTTHUMG00000064919
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: NPA1; C21orf108; KIAA0539

Help top of page

Genomic context

Location :: 21q22.11

Sequence :: Chromosome: 21; NC_000021.8 (33683330..33765312, complement)

See URB1 in Epigenomics, MapViewer

Chromosome 21 - NC_000021.8 Genomic Context describing neighboring genes

Help top of page

Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Help top of page

Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Help top of page

Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

Help top of page

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:115207	BioGRID:111583	MAPK6	BioGRID	PubMed	Two-hybrid
BioGRID:115207	BioGRID:203509	Nhp2l1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115207	BioGRID:115717	TAB1	BioGRID	PubMed	Two-hybrid
BioGRID:115207	BioGRID:113164	UBC	BioGRID	PubMed	Affinity Capture-MS

Function	Evidence Code	Pubs
molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
nucleolus	IDA Inferred from Direct Assay more info	PubMed
nucleolus	NAS Non-traceable Author Statement more info	PubMed
nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: nucleolar pre-ribosomal-associated protein 1

Names: nucleolar pre-ribosomal-associated protein 1; nucleolar protein 254 kDa; nucleolar preribosomal-associated protein 1

Help top of page

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_014825.2 → NP_055640.2 nucleolar pre-ribosomal-associated protein 1

Status: VALIDATED

Source sequence(s)

AP000266, AP000267, AP000268, AP000269

Consensus CDS

CCDS46645.1

UniProtKB/Swiss-Prot

O60287

Related

ENSP00000372199, OTTHUMP00000067386, ENST00000382751, OTTHUMT00000139400

Conserved Domains (1) summary

pfam11707
Location:73 – 394
Blast Score: 638

Npa1; Ribosome 60S biogenesis N-terminal

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000021.8 Reference GRCh37.p5 Primary Assembly

Range

33683330..33765312, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000153.1 Alternate HuRef

Range

19092100..19174182, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Help top of page

Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AP000266.1 (49066..64427)	None
genomic	AP000267.1	None
genomic	AP000268.1	None
genomic	AP000269.2	None
genomic	CH471079.2	EAX09876.1
		EAX09877.1
mRNA	AB011111.2	BAA25465.2
mRNA	AF231919.1	AAF72943.1
mRNA	AF432264.1	AAL28110.1
mRNA	BC041033.1	None
mRNA	BC062356.1	None