These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_033486.1 → NP_277021.1 cyclin-dependent kinase 11B isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an internal coding region when compared to variant 1. It thus encodes an isoform that lacks a 14 aa internal fragment as compared to isoform 1.
- Source sequence(s)
-
AF067512
- UniProtKB/Swiss-Prot
-
P21127
- Conserved Domains (2) summary
-
- cd07843
Location:419 – 710
Blast Score: 1586
- STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
- PLN00009
Location:422 – 712
Blast Score: 768
- PLN00009; cyclin-dependent kinase A; Provisional
-
NM_033487.1 → NP_277022.1 cyclin-dependent kinase 11B isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an internal coding region when compared to variant 1. It encodes an isoform that lacks a 101 aa internal fragment, as compared to isoform 1.
- Source sequence(s)
-
AF067513
- UniProtKB/Swiss-Prot
-
P21127
- Conserved Domains (2) summary
-
- cd07843
Location:163 – 454
Blast Score: 1586
- STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
- PLN00009
Location:166 – 456
Blast Score: 774
- PLN00009; cyclin-dependent kinase A; Provisional
-
NM_033488.1 → NP_277023.1 cyclin-dependent kinase 11B isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an additional 5' internal fragment and lacks two separated internal coding regions when compared to variant 1. The additional fragment leads to a translation frame shift. The resulting protein has a unique first 3 aa and a 37 aa truncation at the N-terminus, and lacks two separated internal fragments, as compared to isoform 1.
- Source sequence(s)
-
AF067514
- UniProtKB/Swiss-Prot
-
P21127
- Conserved Domains (2) summary
-
- cd07843
Location:374 – 665
Blast Score: 1584
- STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
- PLN00009
Location:377 – 667
Blast Score: 767
- PLN00009; cyclin-dependent kinase A; Provisional
-
NM_033489.1 → NP_277024.1 cyclin-dependent kinase 11B isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) contains an additional 5' internal fragment and lacks an internal coding region when compared to variant 1. The additional fragment leads to a translation frame shift. The resulting protein has a unique first 3 aa and a 37 aa truncation at the N-terminus, as well as lacks an internal fragment, as compared to isoform 1.
- Source sequence(s)
-
AF067516
- UniProtKB/Swiss-Prot
-
P21127
- Conserved Domains (2) summary
-
- cd07843
Location:385 – 676
Blast Score: 1587
- STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
- PLN00009
Location:388 – 678
Blast Score: 769
- PLN00009; cyclin-dependent kinase A; Provisional
-
NM_033492.1 → NP_277027.1 cyclin-dependent kinase 11B isoform 8
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) contains an extra coding region and lacks two separated internal coding regions when compared to variant 1. The resulting protein thus contains an additional 9 aa internal fragment, and lacks two separated internal fragments, as compared to isoform 1.
- Source sequence(s)
-
U04816
- UniProtKB/Swiss-Prot
-
P21127
- Conserved Domains (2) summary
-
- cd07843
Location:417 – 708
Blast Score: 1586
- STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
- PLN00009
Location:420 – 710
Blast Score: 769
- PLN00009; cyclin-dependent kinase A; Provisional
-
NM_033493.1 → NP_277028.1 cyclin-dependent kinase 11B isoform 9
Status: REVIEWED
- Description
- Transcript Variant: This variant (9) lacks two separated internal coding regions when compared to variant 1. The resulting protein thus lacks a 11 aa and a 14 aa internal fragment, as compared to isoform 1.
- Source sequence(s)
-
U04817
- UniProtKB/Swiss-Prot
-
P21127
- Conserved Domains (2) summary
-
- cd07843
Location:408 – 699
Blast Score: 1584
- STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
- PLN00009
Location:411 – 701
Blast Score: 768
- PLN00009; cyclin-dependent kinase A; Provisional
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000001.10 Reference GRCh37.p5 Primary Assembly
- Range
- 1571100..1590473, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000133.1 Alternate HuRef
- Range
- 839060..867349, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_001787.1: Suppressed sequence
- Description
- NM_001787.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
-
NM_033490.1: Suppressed sequence
- Description
- NM_033490.1: This RefSeq was permanently suppressed because it contains the wrong CDS. Annotation of the correct CDS leads to this transcript being a nonsense-mediated mRNA decay (NMD) candidate.