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    Deptor DEP domain containing MTOR-interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 97998, updated on 9-May-2013
    Official Symbol
    Deptorprovided by MGI
    Official Full Name
    DEP domain containing MTOR-interacting proteinprovided by MGI
    Primary source
    MGI:2146322
    See related
    Ensembl:ENSMUSG00000022419; Vega:OTTMUSG00000024429
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Depdc6; R75183; mKIAA4200; Depdc6-001; Depdc6-002; D15Ertd336e; D15Ertd597e; 4731402B04Rik; 9130412E02Rik
    Location :
    15 D1; 15 21.96 cM
    Sequence :
    Chromosome: 15; NC_000081.6 (55112483..55254202)
    See Deptor in Epigenomics, MapViewer

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor Neighboring gene defective in sister chromatid cohesion 1 homolog (S. cerevisiae) Neighboring gene predicted gene 9920 Neighboring gene collagen, type XIV, alpha 1 Neighboring gene RIKEN cDNA 1700040F17 gene Neighboring gene RNA binding motif protein, X-linked 2 pseudogene

    Markers

    Homology

    Clone Names

    • KIAA4200

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of TOR signaling cascade ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell size ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    DEP domain-containing mTOR-interacting protein
    Names
    DEP domain-containing mTOR-interacting protein
    DEP domain containing 6
    DEP domain-containing protein 6

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037937.2NP_001033026.1  DEP domain-containing mTOR-interacting protein isoform b

      Status: PROVISIONAL

      Source sequence(s)
      AC124659
      Consensus CDS
      CCDS27475.1
      UniProtKB/TrEMBL
      B2ZRS7
      UniProtKB/Swiss-Prot
      Q570Y9
      Related
      ENSMUSP00000023056, OTTMUSP00000029175, ENSMUST00000023056, OTTMUST00000059893
      Conserved Domains (3) summary
      cd00992
      Location:327391
      Blast Score: 88
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04441
      Location:121204
      Blast Score: 398
      DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
      cl02442
      Location:29105
      Blast Score: 388
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
    2. NM_145470.2NP_663445.2  DEP domain-containing mTOR-interacting protein isoform a

      Status: PROVISIONAL

      Source sequence(s)
      AK220300
      Consensus CDS
      CCDS27474.1
      UniProtKB/TrEMBL
      B2ZRS3
      UniProtKB/Swiss-Prot
      Q570Y9
      Conserved Domains (3) summary
      cd00992
      Location:339403
      Blast Score: 87
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04441
      Location:133216
      Blast Score: 389
      DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
      cd04442
      Location:36117
      Blast Score: 409
      DEP_1_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 1 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p1 C57BL/6J

      Range
      55112483..55254202
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000037.1 Alternate Mm_Celera

      Range
      56652905..56794634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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