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    gag gag protein [ Simian immunodeficiency virus SIV-mnd 2 ]

    Gene ID: 956108, updated on 21-Jan-2012
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    Summary

    Gene symbol
    gag
    Gene description
    gag protein
    Locus tag
    Siv2gp1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Simian immunodeficiency virus SIV-mnd 2 (isolate: SIVmnd-2, nat-host: Mandrillus sphinx, old-name: Simian immunodeficiency virus 2)
    Lineage
    Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus group
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    Genomic context

    Sequence :
    NC_004455.1 (737..2290)

    NC_004455.1Genomic Context describing neighboring genes Neighboring gene protease, RT, RNaseH, integrase Neighboring gene vif protein Neighboring gene vpx protein Neighboring gene vpr protein Neighboring gene tat protein

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Mapping of the self-interaction domains in the simian immunodeficiency virus Gag polyprotein. Rauddi ML, et al. AIDS Res Hum Retroviruses, 2011 Mar. PMID 20969459.
    2. Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1. Zhai Q, et al. J Virol, 2011 Jan. PMID 20962096.
    3. Natural infection of wild-born mandrills (Mandrillus sphinx) with two different types of simian immunodeficiency virus. Takehisa J, et al. AIDS Res Hum Retroviruses, 2001 Aug 10. PMID 11522184.

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. The authors identified the region comprising the C-terminal third portion of the capsid and the entire nucleocapsid as the major SIV Gag interacting domain.
      Title: Mapping of the self-interaction domains in the simian immunodeficiency virus Gag polyprotein.
    2. Crystal structures revealed that anchoring tyrosines and nearby hydrophobic residues contact the ALIX V domain, revealing how SIV gag proteins employ a diverse family of late-domain sequences to bind ALIX and promote virus budding.
      Title: Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1.
    Submit: New GeneRIF Correction
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    General protein information

    Names
    gag protein
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    mRNA and Protein(s)

    1. NP_758886.1 gag protein [Simian immunodeficiency virus SIV-mnd 2]

      UniProtKB/TrEMBL
      Q8Q7J5
      Conserved Domains (4) summary
      pfam00540
      Location:2 – 136
      Blast Score: 432
      Gag_p17; gag gene protein p17 (matrix protein)
      PTZ00368
      Location:396 – 451
      Blast Score: 126
      PTZ00368; universal minicircle sequence binding protein (UMSBP); Provisional
      cl15298
      Location:418 – 435
      Blast Score: 87
      zf-CCHC; Zinc knuckle
      pfam00607
      Location:152 – 361
      Blast Score: 651
      Gag_p24; gag gene protein p24 (core nucleocapsid protein)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AF367411.2 AAM08705.2
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q8Q7J5.1 GenPept

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