ybjG undecaprenyl pyrophosphate phosphatase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: ybjG
Gene description: undecaprenyl pyrophosphate phosphatase
Primary source: ASAP:ABE-0002865
Locus tag: b0841
See related: ECOCYC:G6439
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0831
Summary: The ybjG gene is not essential, but UppP activity is essential to synthesize undecaprenyl phosphate, a C55 lipid carrier for cell wall synthesis, so a ybjG pgpB bacA triple mutant is lethal; overexpression, but not wildtype levels, of the LpxT(YeiU) UppP activity rescues the triple mutant (El Ghachi, 2005). [More information is available at EcoGene: EG13676]. YbjG is similar to a bacitracin resistance protein BcrC of Bacillus licheniformis. [More information is available at EcoCyc: G6439].
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NC_000913.3 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables undecaprenyl-diphosphatase activity	IDA Inferred from Direct Assay more info	PubMed
enables undecaprenyl-diphosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell wall organization	IEA Inferred from Electronic Annotation more info
involved_in peptidoglycan biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info
involved_in response to antibiotic	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to antibiotic	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

NP_415362.1

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The following sections contain reference sequences that belong to a specific genome build. Explain