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SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 [ Homo sapiens (human) ]

Gene ID: 9390, updated on 7-Dec-2014
Official Symbol
SLC22A13provided by HGNC
Official Full Name
solute carrier family 22 (organic anion/urate transporter), member 13provided by HGNC
Primary source
HGNC:HGNC:8494
See related
Ensembl:ENSG00000172940; HPRD:06810; MIM:604047; Vega:OTTHUMG00000131086
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OAT10; OCTL1; OCTL3; ORCTL3; ORCTL-3
Summary
This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine. [provided by RefSeq, Sep 2008]
See SLC22A13 in Epigenomics, MapViewer
Location:
3p21.3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 3 NC_000003.12 (38265807..38278670)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (38307298..38320161)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928234 Neighboring gene oxidative stress responsive 1 Neighboring gene cell division cycle 42 pseudogene Neighboring gene solute carrier family 22, member 14 Neighboring gene deleted in lung and esophageal cancer 1 pseudogene 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
nicotinate transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
organic cation transmembrane transporter activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
nicotinate transport IDA
Inferred from Direct Assay
more info
PubMed 
organic cation transport NAS
Non-traceable Author Statement
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
urate transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular vesicular exosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
solute carrier family 22 member 13
Names
solute carrier family 22 member 13
organic cation transporter-like 3
organic-cation transporter like 3
organic cationic transporter-like 3
solute carrier family 22, member 13
solute carrier family 22 (organic anion transporter), member 13

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004256.3NP_004247.2  solute carrier family 22 member 13

    See proteins identical to NP_004247.2

    Status: REVIEWED

    Source sequence(s)
    AB010438, AK315301, DA629311
    Consensus CDS
    CCDS2676.1
    UniProtKB/Swiss-Prot
    Q9Y226
    Related
    ENSP00000310241, OTTHUMP00000161721, ENST00000311856, OTTHUMT00000253746
    Conserved Domains (2) summary
    cd06174
    Location:139500
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:12510
    2A0119; cation transport protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000003.12 

    Range
    38265807..38278670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_245163.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018914.2 

    Range
    38258992..38271500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000135.1 

    Range
    38349252..38361760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)