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NRXN3 neurexin 3 [ Homo sapiens (human) ]

Gene ID: 9369, updated on 26-May-2016
Official Symbol
NRXN3provided by HGNC
Official Full Name
neurexin 3provided by HGNC
Primary source
HGNC:HGNC:8010
See related
Ensembl:ENSG00000021645 HPRD:08989; MIM:600567; Vega:OTTHUMG00000171502
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf60
Summary
This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]
Orthologs
Location:
14q31
Exon count:
30
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 14 NC_000014.9 (78021758..79868290)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (78636716..80334633)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370581 Neighboring gene aarF domain containing kinase 1 Neighboring gene transfer RNA suppressor (CTA) 3-1 Neighboring gene RNA, 5S ribosomal pseudogene 388 Neighboring gene frataxin pseudogene 1 Neighboring gene ribosomal protein S26 pseudogene 48 Neighboring gene uncharacterized LOC105370589 Neighboring gene uncharacterized LOC105370588 Neighboring gene uncharacterized LOC105370587 Neighboring gene uncharacterized LOC105370586 Neighboring gene uncharacterized LOC105370585 Neighboring gene uncharacterized LOC105370584 Neighboring gene uncharacterized LOC105370583 Neighboring gene uncharacterized LOC105370582 Neighboring gene uncharacterized LOC105370590

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
A genome-wide association study on obesity and obesity-related traits.
NHGRI GWA Catalog
Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.
NHGRI GWA Catalog
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
NHGRI GWA Catalog
Common genetic variation and performance on standardized cognitive tests.
NHGRI GWA Catalog
Gene-Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study.
NHGRI GWA Catalog
Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.
NHGRI GWA Catalog
Genome-wide association studies and heritability estimates of body mass index related phenotypes in bangladeshi adults.
NHGRI GWA Catalog
Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy.
NHGRI GWA Catalog
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
NHGRI GWA Catalog
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.
NHGRI GWA Catalog
  • Cell adhesion molecules (CAMs), organism-specific biosystem (from KEGG)
    Cell adhesion molecules (CAMs), organism-specific biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
  • Cell adhesion molecules (CAMs), conserved biosystem (from KEGG)
    Cell adhesion molecules (CAMs), conserved biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ38928, FLJ44845, KIAA0743, MGC176711

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 
cell adhesion molecule binding TAS
Traceable Author Statement
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
neuroligin family protein binding TAS
Traceable Author Statement
more info
PubMed 
receptor activity TAS
Traceable Author Statement
more info
PubMed 
transmembrane signaling receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
adult behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
axon guidance TAS
Traceable Author Statement
more info
PubMed 
learning IGI
Inferred from Genetic Interaction
more info
PubMed 
neuron cell-cell adhesion TAS
Traceable Author Statement
more info
PubMed 
neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 
positive regulation of synapse assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of synapse maturation IEA
Inferred from Electronic Annotation
more info
 
signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
social behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
synapse assembly IEA
Inferred from Electronic Annotation
more info
 
vocalization behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
presynapse IEA
Inferred from Electronic Annotation
more info
 
protein complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
neurexin 3
Names
neurexin III
neurexin-3-alpha

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105250.2NP_001098720.1  neurexin 3 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001098720.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and contains multiple differences in the coding region, including the lack of multiple 5' exons, compared to variant 1. It initiates translation at an alternate start codon. The encoded isoform (3) is shorter and has a distinct N-terminus, compared to isoform 1. This variant encodes a beta isoform.
    Source sequence(s)
    AF123462, BC150194, DA243312
    Consensus CDS
    CCDS45145.1
    UniProtKB/Swiss-Prot
    Q9HDB5
    Related
    ENSP00000394426, OTTHUMP00000246250, ENST00000428277, OTTHUMT00000413792
    Conserved Domains (2) summary
    cd00110
    Location:86265
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam01034
    Location:385441
    Syndecan; Syndecan domain
  2. NM_001272020.1NP_001258949.1  neurexin 3 isoform 4 precursor

    See identical proteins and their annotated locations for NP_001258949.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and contains multiple differences in the coding region, including the lack of multiple 5' exons, compared to variant 1. It initiates translation at an alternate start codon. The encoded isoform (4) is shorter and has a distinct N-terminus, compared to isoform 1. This variant encodes a beta isoform.
    Source sequence(s)
    AF123462, AK056530, BC150194
    Consensus CDS
    CCDS61515.1
    UniProtKB/Swiss-Prot
    Q9HDB5
    Related
    ENSP00000451672, OTTHUMP00000246248, ENST00000557594, OTTHUMT00000413790
    Conserved Domains (2) summary
    cd00110
    Location:86235
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam01034
    Location:563619
    Syndecan; Syndecan domain
  3. NM_004796.5NP_004787.2  neurexin 3 isoform 1

    See identical proteins and their annotated locations for NP_004787.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC026888, AF123462, BC150194, BC152457, DA213090
    Consensus CDS
    CCDS9870.1
    UniProtKB/Swiss-Prot
    Q9HDB5, Q9Y4C0
    Related
    ENSP00000451648, OTTHUMP00000246246, ENST00000554719, OTTHUMT00000413787
    Conserved Domains (4) summary
    smart00282
    Location:140
    LamG; Laminin G domain
    cd00054
    Location:274307
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:499652
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam01034
    Location:9871043
    Syndecan; Syndecan domain
  4. NM_138970.4NP_620426.2  neurexin 3 isoform 2 precursor

    See identical proteins and their annotated locations for NP_620426.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and contains multiple differences in the coding region, including the lack of multiple 5' exons, compared to variant 1. It initiates translation at an alternate start codon. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1. This variant encodes a beta isoform.
    Source sequence(s)
    AF123462, AK056530, BC059368, BC150194
    Consensus CDS
    CCDS9871.1
    UniProtKB/Swiss-Prot
    Q9HDB5
    Related
    ENSP00000281127, OTTHUMP00000246249, ENST00000281127, OTTHUMT00000413791
    Conserved Domains (2) summary
    cd00110
    Location:86235
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam01034
    Location:358414
    Syndecan; Syndecan domain

RNA

  1. NR_073546.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) contains multiple differences in its 5' and 3' exon structure, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF123462, AJ493127, AK056530, BC150194
  2. NR_073547.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) contains multiple differences in its 5' and 3' exon structure, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF123462, AJ316284, BC150194, DA083962

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p2 Primary Assembly

    Range
    78021758..79868290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011537364.1XP_011535666.1  

    See identical proteins and their annotated locations for XP_011535666.1

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:16131669
    Syndecan; Syndecan domain
  2. XM_011537363.1XP_011535665.1  

    See identical proteins and their annotated locations for XP_011535665.1

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:16131669
    Syndecan; Syndecan domain
  3. XM_011537368.1XP_011535670.1  

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:15121568
    Syndecan; Syndecan domain
  4. XM_011537371.1XP_011535673.1  

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:14051461
    Syndecan; Syndecan domain
  5. XM_005268218.2XP_005268275.1  

    See identical proteins and their annotated locations for XP_005268275.1

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:16101666
    Syndecan; Syndecan domain
  6. XM_011537369.1XP_011535671.1  

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:15091565
    Syndecan; Syndecan domain
  7. XM_011537372.1XP_011535674.1  

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:14021458
    Syndecan; Syndecan domain
  8. XM_011537367.1XP_011535669.1  

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:15831639
    Syndecan; Syndecan domain
  9. XM_011537373.1XP_011535675.1  

    See identical proteins and their annotated locations for XP_011535675.1

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:13721428
    Syndecan; Syndecan domain
  10. XM_011537366.1XP_011535668.1  

    See identical proteins and their annotated locations for XP_011535668.1

    Related
    ENSP00000488920, OTTHUMP00000281268, ENST00000634499, OTTHUMT00000488137
    Conserved Domains (4) summary
    cd00054
    Location:651684
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:262414
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:16051661
    Syndecan; Syndecan domain
  11. XM_011537370.1XP_011535672.1  

    See identical proteins and their annotated locations for XP_011535672.1

    Conserved Domains (4) summary
    cd00054
    Location:651684
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:262414
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:15011557
    Syndecan; Syndecan domain
  12. XM_006720322.2XP_006720385.1  

    Conserved Domains (4) summary
    cd00054
    Location:655688
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8801033
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:16091665
    Syndecan; Syndecan domain
  13. XM_006720323.2XP_006720386.1  

    See identical proteins and their annotated locations for XP_006720386.1

    UniProtKB/TrEMBL
    A0A0U1RRJ0
    Related
    ENSP00000489551, OTTHUMP00000281269, ENST00000635466, OTTHUMT00000488138
    Conserved Domains (4) summary
    cd00054
    Location:647680
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:258410
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:14971553
    Syndecan; Syndecan domain
  14. XM_011537374.1XP_011535676.1  

    Related
    ENSP00000450683, OTTHUMP00000246243, ENST00000554738, OTTHUMT00000413783
    Conserved Domains (3) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
  15. XM_011537375.1XP_011535677.1  

    Conserved Domains (3) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
  16. XM_011537376.1XP_011535678.1  

    Conserved Domains (3) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
  17. XM_011537365.1XP_011535667.1  

    See identical proteins and their annotated locations for XP_011535667.1

    Conserved Domains (4) summary
    cd00054
    Location:659692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:8841037
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:204232
    EGF; EGF-like domain
    pfam01034
    Location:16131669
    Syndecan; Syndecan domain
  18. XM_011537377.1XP_011535679.1  

    Conserved Domains (3) summary
    cd00054
    Location:295328
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:520673
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam01034
    Location:12491305
    Syndecan; Syndecan domain

RNA

  1. XR_943561.1 RNA Sequence

  2. XR_943563.1 RNA Sequence

  3. XR_943562.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018925.2 Alternate CHM1_1.1

    Range
    78576541..80274856
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    GenBank, FASTA, Sequence Viewer (Graphics)