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GPR52 G protein-coupled receptor 52 [ Homo sapiens (human) ]

Gene ID: 9293, updated on 26-May-2016
Official Symbol
GPR52provided by HGNC
Official Full Name
G protein-coupled receptor 52provided by HGNC
Primary source
HGNC:HGNC:4508
See related
Ensembl:ENSG00000203737 HPRD:07247; MIM:604106
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM, Jul 2002]
Orthologs
Location:
1q24
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (174448074..174449545)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (174417212..174418683)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102724601 Neighboring gene RAB GTPase activating protein 1-like Neighboring gene forty-two-three domain containing 1 pseudogene Neighboring gene barrier to autointegration factor 1 pseudogene 4 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 4 pseudogene 4

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of G protein-coupled receptor 52 (GPR52) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

  • GPCRs, Class A Rhodopsin-like, organism-specific biosystem (from WikiPathways)
    GPCRs, Class A Rhodopsin-like, organism-specific biosystemThis pathway was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used ...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC111751

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G-protein coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
dopamine binding IBA
Inferred from Biological aspect of Ancestor
more info
 
dopamine neurotransmitter receptor activity, coupled via Gs IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
adenylate cyclase-activating dopamine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
learning IBA
Inferred from Biological aspect of Ancestor
more info
 
phospholipase C-activating dopamine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
synaptic transmission, dopaminergic IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
probable G-protein coupled receptor 52

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005684.4NP_005675.3  probable G-protein coupled receptor 52

    See identical proteins and their annotated locations for NP_005675.3

    Status: VALIDATED

    Source sequence(s)
    AL022171, BC069460, BC095532, DA174341, DB168074
    Consensus CDS
    CCDS30941.1
    UniProtKB/Swiss-Prot
    Q9Y2T5
    UniProtKB/TrEMBL
    F2YGU0
    Related
    ENSP00000356658, OTTHUMP00000032861, ENST00000367685, OTTHUMT00000084511
    Conserved Domains (1) summary
    pfam00001
    Location:73317
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    174448074..174449545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    175839796..175841267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)