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NEMF nuclear export mediator factor [ Homo sapiens (human) ]

Gene ID: 9147, updated on 8-May-2016
Official Symbol
NEMFprovided by HGNC
Official Full Name
nuclear export mediator factorprovided by HGNC
Primary source
HGNC:HGNC:10663
See related
Ensembl:ENSG00000165525 HPRD:08494; MIM:608378
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NY-CO-1; SDCCAG1
Orthologs
Location:
14q22
Exon count:
37
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 14 NC_000014.9 (49783278..49853073, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (50250528..50319763, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene polymerase (DNA) epsilon 2, accessory subunit Neighboring gene serine/threonine kinase 16 pseudogene 1 Neighboring gene kelch domain containing 1 Neighboring gene kelch domain containing 2 Neighboring gene uncharacterized LOC105378179 Neighboring gene RNA, 7SL, cytoplasmic 3 Neighboring gene RNA, 7SL, cytoplasmic 2

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ10051

Gene Ontology Provided by GOA

Process Evidence Code Pubs
nuclear export IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
nuclear export mediator factor NEMF
Names
antigen NY-CO-1
serologically defined colon cancer antigen 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001301732.1NP_001288661.1  nuclear export mediator factor NEMF isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK295010, AK304695, BC064364, CB112336, DC382921
    UniProtKB/Swiss-Prot
    O60524
    Conserved Domains (4) summary
    COG1293
    Location:1623
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]
    pfam05670
    Location:532585
    DUF814; Domain of unknown function (DUF814)
    pfam11923
    Location:9441047
    DUF3441; Domain of unknown function (DUF3441)
    cl22451
    Location:637755
    ASF1_hist_chap; ASF1 like histone chaperone
  2. NM_004713.4NP_004704.2  nuclear export mediator factor NEMF isoform 1

    See identical proteins and their annotated locations for NP_004704.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK000913, BC064364, BX640807, CB112336, DA899175, DC382921
    Consensus CDS
    CCDS9694.1
    UniProtKB/Swiss-Prot
    O60524
    Related
    ENSP00000298310, OTTHUMP00000244631, ENST00000298310, OTTHUMT00000410798
    Conserved Domains (4) summary
    COG1293
    Location:1644
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]
    pfam05670
    Location:532606
    DUF814; Domain of unknown function (DUF814)
    pfam11923
    Location:9651068
    DUF3441; Domain of unknown function (DUF3441)
    cl22451
    Location:658776
    ASF1_hist_chap; ASF1 like histone chaperone

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p2 Primary Assembly

    Range
    49783278..49853073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005268201.3XP_005268258.1  

    Conserved Domains (4) summary
    COG1293
    Location:49415
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]
    pfam05670
    Location:303377
    DUF814; Domain of unknown function (DUF814)
    pfam11923
    Location:736839
    DUF3441; Domain of unknown function (DUF3441)
    cl22451
    Location:429547
    ASF1_hist_chap; ASF1 like histone chaperone
  2. XM_005268200.3XP_005268257.1  

    See identical proteins and their annotated locations for XP_005268257.1

    Conserved Domains (4) summary
    COG1293
    Location:10430
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]
    pfam05670
    Location:318392
    DUF814; Domain of unknown function (DUF814)
    pfam11923
    Location:751854
    DUF3441; Domain of unknown function (DUF3441)
    cl22451
    Location:444562
    ASF1_hist_chap; ASF1 like histone chaperone
  3. XM_011537316.1XP_011535618.1  

    See identical proteins and their annotated locations for XP_011535618.1

    Conserved Domains (4) summary
    COG1293
    Location:10430
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]
    pfam05670
    Location:318392
    DUF814; Domain of unknown function (DUF814)
    pfam11923
    Location:751854
    DUF3441; Domain of unknown function (DUF3441)
    cl22451
    Location:444562
    ASF1_hist_chap; ASF1 like histone chaperone
  4. XM_011537317.1XP_011535619.1  

    Conserved Domains (2) summary
    COG1293
    Location:1580
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]
    pfam05670
    Location:532582
    DUF814; Domain of unknown function (DUF814)
  5. XM_011537318.1XP_011535620.1  

    Conserved Domains (1) summary
    COG1293
    Location:1400
    YloA; Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains [Translation, ribosomal structure and biogenesis]

RNA

  1. XR_943556.1 RNA Sequence

  2. XR_943557.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018925.2 Alternate CHM1_1.1

    Range
    50189108..50258049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)