These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_029825.1 RefSeqGene
- Range
- 5001..31512
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001243759.1 → NP_001230688.1 ubiquitin carboxyl-terminal hydrolase 2 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an internal exon in the 5' region, compared to variant 1. The resulting isoform (c) has a shorter and different N-terminus compared to isoform a.
- Source sequence(s)
-
AP003396, BC041366, DB065104, DB088349
- UniProtKB/TrEMBL
-
E9PPM2
- UniProtKB/Swiss-Prot
-
O75604
- Conserved Domains (3) summary
-
- cd02674
Location:111 – 354
Blast Score: 647
- Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cl02553
Location:25 – 46
Blast Score: 123
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:21 – 353
Blast Score: 734
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
NM_004205.4 → NP_004196.4 ubiquitin carboxyl-terminal hydrolase 2 isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AI806430, AK057225, BC002955, BC041366, DB065104, DB098786
- Consensus CDS
-
CCDS8422.1
- UniProtKB/Swiss-Prot
-
O75604
- Related
- ENSP00000260187, OTTHUMP00000232156, ENST00000260187, OTTHUMT00000388361
- Conserved Domains (3) summary
-
- cd02674
Location:354 – 597
Blast Score: 657
- Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cl02553
Location:268 – 289
Blast Score: 125
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:264 – 596
Blast Score: 747
- UCH; Ubiquitin carboxyl-terminal hydrolase
-
NM_171997.2 → NP_741994.1 ubiquitin carboxyl-terminal hydrolase 2 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) is missing 2 exons from the 5' end, and contains an alternate 5' terminal exon compared to transcript variant 1. This results in a shorter isoform (b) with a different N-terminus compared to isoform a.
- Source sequence(s)
-
AF440755, AI806430, AK057225, BC041366
- Consensus CDS
-
CCDS8423.1
- UniProtKB/Swiss-Prot
-
O75604
- Related
- ENSP00000436952, OTTHUMP00000232158, ENST00000525735, OTTHUMT00000388363
- Conserved Domains (3) summary
-
- cd02674
Location:145 – 388
Blast Score: 653
- Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cl02553
Location:59 – 80
Blast Score: 124
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:55 – 387
Blast Score: 741
- UCH; Ubiquitin carboxyl-terminal hydrolase
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000011.9 Reference GRCh37.p5 Primary Assembly
- Range
- 119225925..119252436, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000143.1 Alternate HuRef
- Range
- 115167582..115194094, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)