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YIF1B Yip1 interacting factor homolog B, membrane trafficking protein [ Homo sapiens (human) ]

Gene ID: 90522, updated on 8-May-2016
Official Symbol
YIF1Bprovided by HGNC
Official Full Name
Yip1 interacting factor homolog B, membrane trafficking proteinprovided by HGNC
Primary source
HGNC:HGNC:30511
See related
Ensembl:ENSG00000167645 HPRD:11277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FinGER8
Orthologs
Location:
19q13.2
Exon count:
11
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 19 NC_000019.10 (38303560..38315976, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (38794200..38806615, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14A Neighboring gene serine peptidase inhibitor, Kunitz type, 2 Neighboring gene chromosome 19 open reading frame 33 Neighboring gene potassium two pore domain channel subfamily K member 6 Neighboring gene cation channel sperm associated auxiliary subunit gamma

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ23477, FLJ50074, MGC39135

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
protein YIF1B
Names
YIP1-interacting factor homolog B
Yip1 interacting factor homolog B

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039671.2NP_001034760.1  protein YIF1B isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and 5' coding region, compared to variant 5. The resulting isoform (3) has a shorter and distinct N-terminus, compared to isoform 5.
    Source sequence(s)
    AC011479, AK027130, BE877226, BM703847, BX379501, CA487891
    Consensus CDS
    CCDS46066.1
    UniProtKB/TrEMBL
    Q9H5F7
    Related
    ENSP00000329559, OTTHUMP00000268930, ENST00000329420, OTTHUMT00000460518
    Conserved Domains (1) summary
    pfam03878
    Location:57294
    YIF1; YIF1
  2. NM_001039672.2NP_001034761.1  protein YIF1B isoform 5

    See identical proteins and their annotated locations for NP_001034761.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) encodes the longest isoform (5).
    Source sequence(s)
    AC011479, AK027130, AW630507, BC091477
    Consensus CDS
    CCDS33010.1
    UniProtKB/Swiss-Prot
    Q5BJH7
    UniProtKB/TrEMBL
    Q9H5F7
    Related
    ENSP00000343435, OTTHUMP00000268925, ENST00000339413, OTTHUMT00000460511
    Conserved Domains (1) summary
    pfam03878
    Location:72309
    YIF1; YIF1
  3. NM_001039673.2NP_001034762.1  protein YIF1B isoform 4

    See identical proteins and their annotated locations for NP_001034762.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, compared to variant 5. The resulting isoform (4) lacks a 3-aa segment near the N-terminus, compared to isoform 5.
    Source sequence(s)
    AC011479, AK027130, AW630507, BC007644
    UniProtKB/Swiss-Prot
    Q5BJH7
    UniProtKB/TrEMBL
    Q9H5F7
    Conserved Domains (1) summary
    pfam03878
    Location:69306
    YIF1; YIF1
  4. NM_001145461.1NP_001138933.1  protein YIF1B isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and 5' coding region, compared to variant 5. The resulting isoform (6) has a shorter and distinct N-terminus, compared to isoform 5.
    Source sequence(s)
    AC011479, AK027130, BM703847, CA487891, CA488303
    UniProtKB/TrEMBL
    Q9H5F7
    Conserved Domains (1) summary
    pfam03878
    Location:55292
    YIF1; YIF1
  5. NM_001145462.1NP_001138934.1  protein YIF1B isoform 2

    See identical proteins and their annotated locations for NP_001138934.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 5. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 5.
    Source sequence(s)
    AC011479, AK027130, BC091477, BM703847, CF127536
    Consensus CDS
    CCDS12512.1
    UniProtKB/Swiss-Prot
    Q5BJH7
    UniProtKB/TrEMBL
    Q9H5F7
    Related
    ENSP00000465230, OTTHUMP00000268931, ENST00000591784, OTTHUMT00000460519
    Conserved Domains (1) summary
    pfam03878
    Location:41278
    YIF1; YIF1
  6. NM_001145463.1NP_001138935.1  protein YIF1B isoform 7

    See identical proteins and their annotated locations for NP_001138935.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) uses an alternate in-frame splice site in the 5' coding region and includes an additional exon that results in a frameshift in the 3' coding region, compared to variant 5. The resulting isoform (7) lacks a 3-aa segment near the N-terminus and has a shorter and distinct C-terminus, compared to isoform 5.
    Source sequence(s)
    AC011479, AK027130, AL833382, AW630507
    Consensus CDS
    CCDS46067.1
    UniProtKB/Swiss-Prot
    Q5BJH7
    UniProtKB/TrEMBL
    Q9H5F7
    Related
    ENSP00000337411, OTTHUMP00000268923, ENST00000337679, OTTHUMT00000460508
    Conserved Domains (1) summary
    pfam03878
    Location:69284
    YIF1; YIF1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p2 Primary Assembly

    Range
    38303560..38315976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005259385.2XP_005259442.1  

    See identical proteins and their annotated locations for XP_005259442.1

    UniProtKB/Swiss-Prot
    Q5BJH7
    Related
    ENSP00000466428, OTTHUMP00000268922, ENST00000592694, OTTHUMT00000460507
    Conserved Domains (1) summary
    pfam03878
    Location:41278
    YIF1; YIF1
  2. XM_011527467.1XP_011525769.1  

    See identical proteins and their annotated locations for XP_011525769.1

    UniProtKB/Swiss-Prot
    Q5BJH7
    Related
    ENSP00000465446, OTTHUMP00000268928, ENST00000591755, OTTHUMT00000460514
    Conserved Domains (1) summary
    pfam03878
    Location:69284
    YIF1; YIF1

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 Alternate CHM1_1.1

    Range
    38794553..38806965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001013617.1: Suppressed sequence

    Description
    NM_001013617.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
  2. NM_001031731.1: Suppressed sequence

    Description
    NM_001031731.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  3. NM_033557.3: Suppressed sequence

    Description
    NM_033557.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript, which may retain intronic sequence at its 5' end.