Display Settings:

Format

Send to:

Choose Destination

C15orf57 chromosome 15 open reading frame 57 [ Homo sapiens (human) ]

Gene ID: 90416, updated on 26-Aug-2014
Official Symbol
C15orf57provided by HGNC
Official Full Name
chromosome 15 open reading frame 57provided by HGNC
Primary source
HGNC:28295
See related
Ensembl:ENSG00000128891; HPRD:14473; Vega:OTTHUMG00000129993
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCDC32
See C15orf57 in Epigenomics, MapViewer
Location:
15q15.1
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 15 NC_000015.10 (40531341..40565057, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (40824083..40857252, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 Neighboring gene ribosomal protein L9 pseudogene 27 Neighboring gene mitochondrial ribosomal protein L42 pseudogene 5 Neighboring gene RNA pseudouridylate synthase domain containing 2 Neighboring gene transfer RNA-Ser (GCT) 4-1

Protein interactions

Protein Gene Interaction Pubs
integrase gag-pol Using acetylated HIV-1 IN as bait in yeast two-hybrid screening identifies CCDC32 as IN-binding partner PubMed

Go to the HIV-1, Human Protein Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ25915, MGC20481
Preferred Names
uncharacterized protein C15orf57
Names
uncharacterized protein C15orf57
coiled-coil domain containing 32

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080791.2NP_001074260.1  uncharacterized protein C15orf57 isoform 1

    See proteins identical to NP_001074260.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC091045, AK092214, BC001673, BP289634, BU657334, BX404085, M79093
    Consensus CDS
    CCDS42022.1
    UniProtKB/Swiss-Prot
    Q9BV29
    Conserved Domains (1) summary
    pfam14989
    Location:26176
    Blast Score: 497
    CCDC32; Coiled-coil domain containing 32
  2. NM_001080792.2NP_001074261.1  uncharacterized protein C15orf57 isoform 2

    See proteins identical to NP_001074261.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate donor splice site at the 5' terminal exon and initiates translation from an in-frame downstream start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AC091045, AK312842, BC001673, BP289634, BU657334, BX404085, M79093
    Consensus CDS
    CCDS10060.1
    UniProtKB/Swiss-Prot
    Q9BV29
    Related
    ENSP00000397515, OTTHUMP00000248530, ENST00000416810, OTTHUMT00000418767
    Conserved Domains (1) summary
    pfam14989
    Location:17167
    Blast Score: 493
    CCDC32; Coiled-coil domain containing 32
  3. NM_001289132.1NP_001276061.1  uncharacterized protein C15orf57 isoform 3

    See proteins identical to NP_001276061.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate donor splice site at the 5' terminal exon (which results in translation initiation translation from an in-frame downstream start codon) and contains an alternate 3' terminal exon (which causes a frame-shift) compared to variant 1. The resulting isoform (3) has shorter N- and C- termini compared to isoform 1.
    Source sequence(s)
    AC091045, AK098781, BC012189, BP289634
    Consensus CDS
    CCDS73706.1
    UniProtKB/Swiss-Prot
    Q9BV29
    Related
    ENSP00000454049, OTTHUMP00000248528, ENST00000561011, OTTHUMT00000418765
    Conserved Domains (1) summary
    pfam14989
    Location:17133
    Blast Score: 371
    CCDC32; Coiled-coil domain containing 32
  4. NM_052849.3NP_443081.1  uncharacterized protein C15orf57 isoform 2

    See proteins identical to NP_443081.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate donor splice site at the 5' terminal exon and initiates translation from an in-frame downstream start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AC091045, BC001673, BP289634, BU657334, BX404085, M79093
    Consensus CDS
    CCDS10060.1
    UniProtKB/Swiss-Prot
    Q9BV29
    Related
    ENSP00000350695, OTTHUMP00000160454, ENST00000358005, OTTHUMT00000252259
    Conserved Domains (1) summary
    pfam14989
    Location:17167
    Blast Score: 493
    CCDC32; Coiled-coil domain containing 32

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000015.10 

    Range
    40531341..40565057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000147.1 

    Range
    17667142..17704035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018926.2 

    Range
    40943654..40977338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)