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TPD52L3 tumor protein D52 like 3 [ Homo sapiens (human) ]

Gene ID: 89882, updated on 26-Jul-2016
Official Symbol
TPD52L3provided by HGNC
Official Full Name
tumor protein D52 like 3provided by HGNC
Primary source
HGNC:HGNC:23382
See related
Ensembl:ENSG00000170777 HPRD:14864; Vega:OTTHUMG00000019518
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hD55; NYDSP25
Summary
This gene encodes a member of the tumor protein D52-like family of proteins. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. The encoded protein may play a role in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Orthologs
Location:
9p24.1
Exon count:
2
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 9 NC_000009.12 (6328349..6331900)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (6328349..6331900)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107987046 Neighboring gene interleukin 33 Neighboring gene selenoprotein T pseudogene Neighboring gene ubiquitin like with PHD and ring finger domains 2 Neighboring gene glycine decarboxylase Neighboring gene ribosomal protein L23a pseudogene 57

NHGRI GWAS Catalog

Description
Genome-wide association study of periodontal pathogen colonization.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC26757, MGC45374

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Preferred Names
tumor protein D55
Names
protein kinase NYD-SP25
testis development protein NYD-SP25
testis tissue sperm-binding protein Li 87P
tumor protein D52-like 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001874.2NP_001001874.1  tumor protein D55 isoform 2

    See identical proteins and their annotated locations for NP_001001874.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has an alternate 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2 which has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AL133480, BC033792, BP369721
    Consensus CDS
    CCDS34984.1
    UniProtKB/Swiss-Prot
    Q96J77
    UniProtKB/TrEMBL
    A0A140VKH0
    Related
    ENSP00000318665, OTTHUMP00000021043, ENST00000314556, OTTHUMT00000051659
    Conserved Domains (1) summary
    pfam04201
    Location:2130
    TPD52; tumor protein D52 family
  2. NM_001001875.3NP_001001875.1  tumor protein D55 isoform 3

    See identical proteins and their annotated locations for NP_001001875.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an internal segment, as compared to variant 1. It encodes isoform 3 which has a shorter and distinct C-terminus, as compared to isoform 1.
    Source sequence(s)
    AL133480, BC017589, BP369721, DB507802
    Consensus CDS
    CCDS34985.1
    UniProtKB/Swiss-Prot
    Q96J77
    Related
    ENSP00000370836, OTTHUMP00000021044, ENST00000381428, OTTHUMT00000051660
    Conserved Domains (1) summary
    pfam04201
    Location:2123
    TPD52; tumor protein D52 family
  3. NM_033516.5NP_277051.3  tumor protein D55 isoform 1

    See identical proteins and their annotated locations for NP_277051.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK057479, AL133480, BP369721
    Consensus CDS
    CCDS34986.1
    UniProtKB/Swiss-Prot
    Q96J77
    Related
    ENSP00000341677, OTTHUMP00000021042, ENST00000344545, OTTHUMT00000051658
    Conserved Domains (1) summary
    pfam04201
    Location:2138
    TPD52; tumor protein D52 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p7 Primary Assembly

    Range
    6328349..6331900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015280.1XP_016870769.1  

Alternate CHM1_1.1

Genomic

  1. NC_018920.2 Alternate CHM1_1.1

    Range
    6329148..6332699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)