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RRP36 ribosomal RNA processing 36 [ Homo sapiens (human) ]

Gene ID: 88745, updated on 26-May-2016
Official Symbol
RRP36provided by HGNC
Official Full Name
ribosomal RNA processing 36provided by HGNC
Primary source
HGNC:HGNC:21374
See related
Ensembl:ENSG00000124541 HPRD:12859; MIM:613475; Vega:OTTHUMG00000014715
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf153; dJ20C7.4
Summary
RRP36 functions at an early stage in the processing of 35S preribosomal RNA into the mature 18S species (Gerus et al., 2010 [PubMed 20038530]).[supplied by OMIM, Jul 2010]
Orthologs
Location:
6p21.1
Exon count:
7
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 6 NC_000006.12 (43021636..43029599)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (42989385..42997337)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene male-enhanced antigen 1 Neighboring gene protein phosphatase 2 regulatory subunit B'delta Neighboring gene kelch domain containing 3 Neighboring gene cullin 7 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene kinesin light chain 4

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Major pathway of rRNA processing in the nucleolus, organism-specific biosystem (from REACTOME)
    Major pathway of rRNA processing in the nucleolus, organism-specific biosystemIn humans, a 47S precursor rRNA (pre-rRNA) is transcribed by RNA polymerase I from rRNA-encoding genes (rDNA) at the boundary of the fibrillar center and the dense fibrillar components of the nucleol...
  • rRNA modification in the nucleus, organism-specific biosystem (from REACTOME)
    rRNA modification in the nucleus, organism-specific biosystemHuman ribosomal RNAs (rRNAs) contain about 200 residues that are enzymatically modified after transcription in the nucleolus (Maden and Khan 1977, Maden 1988, Maden and Hughes 1997, reviewed in Herna...
  • rRNA processing, organism-specific biosystem (from REACTOME)
    rRNA processing, organism-specific biosystemEach eukaryotic cytosolic ribosome contains 4 molecules of RNA: 28S rRNA (25S rRNA in yeast), 5.8S rRNA, and 5S rRNA in the 60S subunit and 18S rRNA in the 40S subunit. The 18S rRNA, 5.8S rRNA, and 2...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
cleavage involved in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
 
rRNA processing IDA
Inferred from Direct Assay
more info
PubMed 
rRNA processing TAS
Traceable Author Statement
more info
 
ribosomal small subunit biogenesis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
Preferred Names
ribosomal RNA processing protein 36 homolog
Names
RNA processing factor
ribosomal RNA processing 36 homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033112.2NP_149103.1  ribosomal RNA processing protein 36 homolog

    See identical proteins and their annotated locations for NP_149103.1

    Status: PROVISIONAL

    Source sequence(s)
    BC011933
    Consensus CDS
    CCDS34453.1
    UniProtKB/Swiss-Prot
    Q96EU6
    Related
    ENSP00000244496, OTTHUMP00000016415, ENST00000244496, OTTHUMT00000040572
    Conserved Domains (1) summary
    pfam06102
    Location:91252
    DUF947; Domain of unknown function (DUF947)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p2 Primary Assembly

    Range
    43021636..43029599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_926324.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018917.2 Alternate CHM1_1.1

    Range
    42991838..42999788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)