Format

Send to:

Choose Destination

NOL4 nucleolar protein 4 [ Homo sapiens (human) ]

Gene ID: 8715, updated on 8-May-2016
Official Symbol
NOL4provided by HGNC
Official Full Name
nucleolar protein 4provided by HGNC
Primary source
HGNC:HGNC:7870
See related
Ensembl:ENSG00000101746 HPRD:04657; MIM:603577; Vega:OTTHUMG00000132291
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NOLP; CT125; HRIHFB2255
Orthologs
Location:
18q12
Exon count:
20
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 18 NC_000018.10 (33851100..34224834, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (31431064..31803515, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372059 Neighboring gene coiled-coil domain containing 178 Neighboring gene additional sex combs like 3, transcriptional regulator Neighboring gene uncharacterized LOC105372060 Neighboring gene ribosomal protein L10a pseudogene 13 Neighboring gene dystrobrevin alpha Neighboring gene uncharacterized LOC105372062

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
A genomewide association study of citalopram response in major depressive disorder.
NHGRI GWA Catalog
Genetic variants associated with breast size also influence breast cancer risk.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
Preferred Names
nucleolar protein 4
Names
cancer/testis antigen 125
nucleolar localized protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198546.1NP_001185475.1  nucleolar protein 4 isoform 2

    See identical proteins and their annotated locations for NP_001185475.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AA430033, AB017800, AK297185, BC000313, BM973283, CA865522, CK822635
    UniProtKB/Swiss-Prot
    O94818
    UniProtKB/TrEMBL
    B4DLW2
    Related
    ENSP00000467629, OTTHUMP00000259507, ENST00000590712, OTTHUMT00000442115
  2. NM_001198547.1NP_001185476.1  nucleolar protein 4 isoform 3

    See identical proteins and their annotated locations for NP_001185476.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate, in-frame 5' terminal exon and uses an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AA430033, AK299850, BC000313, BM973283, CA865522, CK822635, DC375356
    Consensus CDS
    CCDS56059.1
    UniProtKB/Swiss-Prot
    O94818
    Related
    ENSP00000443472, OTTHUMP00000259506, ENST00000538587, OTTHUMT00000442114
  3. NM_001198548.1NP_001185477.1  nucleolar protein 4 isoform 4

    See identical proteins and their annotated locations for NP_001185477.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two alternate in-frame exons in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 4), compared to isoform 1.
    Source sequence(s)
    AA430033, AB017800, BC000313, BM973283, CA865522, CK822635
    Consensus CDS
    CCDS59308.1
    UniProtKB/Swiss-Prot
    O94818
    Related
    ENSP00000465450, OTTHUMP00000259505, ENST00000589544, OTTHUMT00000442113
  4. NM_001198549.1NP_001185478.1  nucleolar protein 4 isoform 5

    See identical proteins and their annotated locations for NP_001185478.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (5) is shorter than isoform 1.
    Source sequence(s)
    AA430033, AK296539, BC000313, BM973283, CA865522, CK822635, DC350556
    Consensus CDS
    CCDS56058.1
    UniProtKB/Swiss-Prot
    O94818
    Related
    ENSP00000445733, OTTHUMP00000259503, ENST00000535384, OTTHUMT00000442111
  5. NM_001282527.1NP_001269456.1  nucleolar protein 4 isoform 6

    See identical proteins and their annotated locations for NP_001269456.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) uses an alternate 5' exon structure, and thus differs in the 5' UTR and 5' coding region, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (6) that is shorter, compared to isoform 1.
    Source sequence(s)
    AA430033, AK091463, BC000313, BM973283, CA865522, CK822635, DC375356
    UniProtKB/Swiss-Prot
    O94818
    UniProtKB/TrEMBL
    B3KRF4
  6. NM_003787.4NP_003778.2  nucleolar protein 4 isoform 1

    See identical proteins and their annotated locations for NP_003778.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AA430033, AB017800, BC000313, BM973283, CA865522, CK822635
    Consensus CDS
    CCDS11907.2
    UniProtKB/Swiss-Prot
    O94818
    Related
    ENSP00000261592, OTTHUMP00000163129, ENST00000261592, OTTHUMT00000255386

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p2 Primary Assembly

    Range
    33851100..34224834 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526238.1XP_011524540.1  

    See identical proteins and their annotated locations for XP_011524540.1

    UniProtKB/Swiss-Prot
    O94818
  2. XM_011526237.1XP_011524539.1  

    See identical proteins and their annotated locations for XP_011524539.1

    UniProtKB/Swiss-Prot
    O94818
  3. XM_006722563.2XP_006722626.1  

    See identical proteins and their annotated locations for XP_006722626.1

    UniProtKB/Swiss-Prot
    O94818
  4. XM_006722564.1XP_006722627.1  

    See identical proteins and their annotated locations for XP_006722627.1

  5. XM_006722565.1XP_006722628.1  

    See identical proteins and their annotated locations for XP_006722628.1

  6. XM_011526239.1XP_011524541.1  

    See identical proteins and their annotated locations for XP_011524541.1

  7. XM_011526240.1XP_011524542.1  

    See identical proteins and their annotated locations for XP_011524542.1

  8. XM_006722566.1XP_006722629.1  

    See identical proteins and their annotated locations for XP_006722629.1

  9. XM_011526241.1XP_011524543.1  

RNA

  1. XR_935261.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018929.2 Alternate CHM1_1.1

    Range
    31358224..31730679 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)