These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_004301.3 → NP_004292.1 actin-like protein 6A isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (a), which is also referred to as hArpNbeta/Baf53. Isoform a is found mostly in the nucleus.
- Source sequence(s)
-
AB060168, BC036371
- Consensus CDS
-
CCDS3231.1
- UniProtKB/Swiss-Prot
-
O96019
- Related
- ENSP00000397552, OTTHUMP00000212444, ENST00000429709, OTTHUMT00000349599
- Conserved Domains (2) summary
-
- cd00012
Location:13 – 427
Blast Score: 1022
- ACTIN; Actin; An ubiquitous protein involved in the formation of filaments that are a major component of the cytoskeleton. Interaction with myosin provides the basis of muscular contraction and many aspects of cell motility. Each actin protomer binds one ...
- pfam00022
Location:9 – 429
Blast Score: 1299
- Actin; Actin
-
NM_177989.2 → NP_817126.1 actin-like protein 6A isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region that results in the use of a downstream start codon, compared to variant 1. Variants 2 and 3 both encode isoform b, which has a shorter N-terminus when compared to isoform a. This variant is also known as Nbeta2 and isoform b is also known as hArpNbetaS. Isoform b is found mostly in the cytoplasm.
- Source sequence(s)
-
AB060168, BC036371
- Consensus CDS
-
CCDS43174.1
- UniProtKB/Swiss-Prot
-
O96019
- Related
- ENSP00000394014, OTTHUMP00000212445, ENST00000450518, OTTHUMT00000349600
- Conserved Domains (2) summary
-
- cd00012
Location:15 – 385
Blast Score: 927
- ACTIN; Actin; An ubiquitous protein involved in the formation of filaments that are a major component of the cytoskeleton. Interaction with myosin provides the basis of muscular contraction and many aspects of cell motility. Each actin protomer binds one ...
- smart00268
Location:15 – 386
Blast Score: 1052
- ACTIN; Actin
-
NM_178042.2 → NP_829888.1 actin-like protein 6A isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region that results in the use of a downstream start codon, compared to variant 1. Variants 2 and 3 both encode isoform b, which has a shorter N-terminus when compared to isoform a. This variant is also known as Nbeta3 and isoform b is also known as hArpNbetaS. Isoform b is found mostly in the cytoplasm.
- Source sequence(s)
-
AA256726, AB060168, AB061315, BC036371
- Consensus CDS
-
CCDS43174.1
- UniProtKB/Swiss-Prot
-
O96019
- Related
- ENSP00000376430, ENST00000392662
- Conserved Domains (2) summary
-
- cd00012
Location:15 – 385
Blast Score: 927
- ACTIN; Actin; An ubiquitous protein involved in the formation of filaments that are a major component of the cytoskeleton. Interaction with myosin provides the basis of muscular contraction and many aspects of cell motility. Each actin protomer binds one ...
- smart00268
Location:15 – 386
Blast Score: 1052
- ACTIN; Actin
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000003.11 Reference GRCh37.p5 Primary Assembly
- Range
- 179280708..179306193
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000135.1 Alternate HuRef
- Range
- 176684454..176709974
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)