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    YRF1-2 Yrf1-2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856940, updated on 21-May-2012
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    Summary

    Gene symbol
    YRF1-2
    Gene description
    Yrf1-2p
    Primary source
    SGD:S000000992
    Locus tag
    YER190W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YRF1
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    Genomic context

    Location :
    chromosome: V
    Sequence :
    Chromosome: V; NC_001137.3 (571480..576525)
    See YRF1-2 in MapViewer

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Scherrer T, et al. Genome Biol, 2011. PMID 21232131.
    2. Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. Hasegawa Y, et al. RNA, 2008 Nov. PMID 18805955.
    3. Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. Yamada M, et al. J Biol Chem, 1998 Dec 11. PMID 9837911.
    4. The nucleotide sequence of Saccharomyces cerevisiae chromosome V. Dietrich FS, et al. Nature, 1997 May 29. PMID 9169868.
    5. Life with 6000 genes. Goffeau A, et al. Science, 1996 Oct 25. PMID 8849441.

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36943 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36943 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
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    General gene information

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    ATP-dependent helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    telomere maintenance via recombination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
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    General protein information

    Names
    Yrf1-2p
    NP_011117.1
    • Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; induced by treatment with 8-methoxypsoralen and UVA irradiation
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3

      Range
      571480..576525
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179080.1 → NP_011117.1  Yrf1-2p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P40105
      Conserved Domains (2) summary
      cd00046
      Location:691 – 841
      Blast Score: 109
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:924 – 1028
      Blast Score: 154
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006939.2 DAA07853.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40105.2 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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