Display Settings:

Format

Send to:

Choose Destination

RPH1 Rph1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 856916, updated on 22-Mar-2015
Gene symbol
RPH1
Gene description
Rph1p
Primary source
SGD:S000000971
Locus tag
YER169W
Gene type
protein coding
RNA name
Rph1p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
KDM4
See RPH1 in MapViewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (523369..525759)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Bck2p Neighboring gene Cca1p Neighboring gene adenylate kinase ADK2 Neighboring gene TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Process Evidence Code Pubs
histone demethylation IDA
Inferred from Direct Assay
more info
PubMed 
histone demethylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Rph1p
NP_011096.1
  • JmjC domain-containing histone demethylase; specifically demethylates H3K36 tri- and dimethyl modification states; associates with actively transcribed (RNAP II) regions in vivo and specifically targets H3K36 in its trimethylation state as its substrate; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway; target of stess-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    523369..525759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179059.1NP_011096.1  Rph1p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011096.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P39956
    Conserved Domains (4) summary
    smart00545
    Location:1354
    JmjN; Small domain found in the jumonji family of transcription factors
    pfam02373
    Location:222338
    JmjC; JmjC domain, hydroxylase
    pfam13465
    Location:723749
    zf-H2C2_2; Zinc-finger double domain
    sd00019
    Location:711757
    ZF_C2H2; Zinc finger, C2H2 type