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CHD1 chromatin-remodeling ATPase CHD1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 856911, updated on 5-Jun-2016
Gene symbol
CHD1
Gene description
chromatin-remodeling ATPase CHD1
Primary source
SGD:S000000966
Locus tag
YER164W
Gene type
protein coding
RNA name
chromatin-remodeling ATPase CHD1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See CHD1 in Map Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (505392..509798)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Rad4p Neighboring gene gamma-glutamylcyclotransferase Neighboring gene polyadenylate-binding protein Neighboring gene aminophospholipid-translocating P4-type ATPase DNF1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
chromatin DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
methylated histone binding IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
rDNA binding IDA
Inferred from Direct Assay
more info
PubMed 
transcription regulatory region DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
ATP-dependent chromatin remodeling IDA
Inferred from Direct Assay
more info
PubMed 
chromatin modification IEA
Inferred from Electronic Annotation
more info
 
histone H2B conserved C-terminal lysine ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of DNA-dependent DNA replication IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of histone H3-K14 acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of histone H3-K9 acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of histone exchange IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleosome mobilization IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleosome positioning IDA
Inferred from Direct Assay
more info
PubMed 
regulation of chromatin organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of nucleosome density IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
regulation of transcriptional start site selection at RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
termination of RNA polymerase I transcription IGI
Inferred from Genetic Interaction
more info
PubMed 
termination of RNA polymerase II transcription IGI
Inferred from Genetic Interaction
more info
PubMed 
termination of RNA polymerase II transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription elongation from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
transcription elongation from RNA polymerase II promoter IPI
Inferred from Physical Interaction
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
SAGA complex IDA
Inferred from Direct Assay
more info
PubMed 
SLIK (SAGA-like) complex IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nucleolar chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
chromatin-remodeling ATPase CHD1
NP_011091.1
  • Chromatin remodeler that regulates various aspects of transcription; acts in in conjunction with Isw1b to regulate chromatin structure and maintain chromatin integrity during transcription elongation by RNAP II by preventing trans-histone exchange over coding regions; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    505392..509798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179054.1NP_011091.1  chromatin-remodeling ATPase CHD1 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_011091.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32657
    Conserved Domains (7) summary
    smart00717
    Location:11741198
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    pfam13907
    Location:13621462
    DUF4208; Domain of unknown function (DUF4208)
    cd11660
    Location:11751204
    SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
    cd00024
    Location:282341
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:396544
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:693817
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:379665
    SNF2_N; SNF2 family N-terminal domain