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    BEM2 Bem2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856899, updated on 6-May-2012

    Summary

    Gene symbol
    BEM2
    Gene description
    Bem2p
    Primary source
    SGD:S000000957
    Locus tag
    YER155C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    IPL2; SUP9; TSL1

    Genomic context

    Location :
    chromosome: V
    Sequence :
    Chromosome: V; NC_001137.3 (476345..482848, complement)
    See BEM2 in MapViewer

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Pet122p Neighboring gene Oxa1p Neighboring gene hypothetical protein Neighboring gene Cog3p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36905 BioGRID:31107 ACT1    BioGRID  PubMed Negative Genetic; Synthetic Haploinsufficiency; Synthetic Lethality 
    BioGRID:36905 BioGRID:35854 ALG12    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32690 ALK2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:36693 ANP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34639 APC5    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32929 ARC40    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:36440 ARD1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31853 ARF1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32183 ARO1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32027 ARP2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:31358 ARP6    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:36212 ARP7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:31509 ARV1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34456 ASE1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:34851 AXL2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32897 BEM1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:36066 BEM3    BioGRID  PubMed Dosage Rescue; Negative Genetic; Phenotypic Enhancement; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36022 BEM4    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:36749 BIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36930 BMH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35569 BNI1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:35605 BNI4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32619 BOI1    BioGRID  PubMed Two-hybrid 
    BioGRID:36905 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:36905 BioGRID:31121 BST1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31798 BUD14    BioGRID  PubMed Affinity Capture-MS; Negative Genetic; Two-hybrid 
    BioGRID:36905 BioGRID:34041 BUD2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31583 BUD6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35454 BUL1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34125 CAP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34956 CAP2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35668 CBK1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:31383 CCW12    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32620 CDC27    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32859 CDC28    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:31579 CDC3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31499 CDC42    BioGRID  PubMed Biochemical Activity 
    BioGRID:36905 BioGRID:33066 CDC55    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36905 BioGRID:31676 CDC73    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33242 CDH1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:36905 BioGRID:33121 CEG1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:33217 CGR1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:31594 CHS5    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:33658 CHS6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36575 CHS7    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35376 CIK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36668 CIN8    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:34460 CKA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:33227 CKB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32835 CKS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35540 CLA4    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:33419 CLC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35377 CLN1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:35907 CLN2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:32813 CMD1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35783 COG6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31945 CYK3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34447 DBP5    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:33988 DBR1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:31753 DEP1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:34479 DIA2    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:33952 DOA1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36833 DOT6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35002 DSN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35690 EAF7    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32780 ECM33    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33978 ELF1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35492 ELP6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31122 EPL1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:32473 ERD1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36434 ERG11    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:35380 ERG2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35161 ERG6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33193 ERV14    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32186 FIN1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:36905 BioGRID:31604 FKS1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:36491 FYV4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35487 GAS1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36905 BioGRID:32336 GCN2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33503 GCN5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:31884 GCS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33226 GET1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36493 GIC1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36905 BioGRID:35676 GIM3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:36728 GIM4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:35049 GIM5    BioGRID  PubMed Negative Genetic; Positive Genetic; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36622 GPI16    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33844 GRR1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36905 BioGRID:33166 GUP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32710 HHF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35797 HHF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32711 HHT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35796 HHT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:33831 HOC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35923 HSP82    BioGRID  PubMed Affinity Capture-MS; Synthetic Lethality 
    BioGRID:36905 BioGRID:32277 HTA1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:33933 HYM1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:34902 ICE2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31643 IKI3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33874 ILM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32179 INO2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34321 IRA2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31295 IRC25    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31947 IWR1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:36234 JID1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35474 JNM1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:36310 KAR3    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:30960 KCC4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36592 KEL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35518 KRE1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:35531 KRI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:36517 KSP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34023 KTI12    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33692 LAS21    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36125 LGE1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34058 LHS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33632 LSM1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:32437 LSM6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33729 MAD2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:33540 MAL12    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:34326 MDM20    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:35288 MED11    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32049 MED2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34568 MED4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32890 MED8    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:31584 MMS22    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:33579 MNN11    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32718 MNN2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32659 MRPL16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32946 MRPS5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34465 MSA1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34583 MSB1    BioGRID  PubMed Dosage Rescue; Synthetic Lethality; Synthetic Rescue 
    BioGRID:36905 BioGRID:32392 MSN5    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31731 MTW1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35011 MUC1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36905 BioGRID:36454 MYO1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:34711 MYO2    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36905 BioGRID:32213 NBP2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33045 NCS6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32052 NHP10    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35715 NOP15    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35762 NOP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:31946 NUP84    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:33829 OPI3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32764 ORC2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31612 ORM2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34658 PAC1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:33320 PAC10    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:32540 PAC11    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35548 PCL1    BioGRID  PubMed Phenotypic Enhancement; Synthetic Lethality 
    BioGRID:36905 BioGRID:31936 PCL2    BioGRID  PubMed Phenotypic Enhancement; Synthetic Lethality 
    BioGRID:36905 BioGRID:31026 PER1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33222 PGD1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36147 PHO85    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:33383 PRE9    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34897 PRK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:36905 BioGRID:34746 PRT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35633 PSY2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32048 PTC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34221 PXL1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36692 RAD23    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35137 RAD52    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31999 RAD59    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35620 RAP1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:32078 REG1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32962 REI1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:35527 RFA2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34522 RGA1    BioGRID  PubMed Negative Genetic; Synthetic Lethality; Synthetic Rescue 
    BioGRID:36905 BioGRID:32956 RGD1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36338 RHO1    BioGRID  PubMed Dosage Rescue; Synthetic Lethality 
    BioGRID:36905 BioGRID:35734 RHO2    BioGRID  PubMed Dosage Rescue 
    BioGRID:36905 BioGRID:35652 RHO5    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36905 BioGRID:35629 RIO2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:36153 RMI1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31631 ROM2    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement; Synthetic Growth Defect; Synthetic Rescue 
    BioGRID:36905 BioGRID:33992 RPC25    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34127 RPL14A    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36634 RPN10    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32035 RPN4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31602 RPP0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35103 RPS1B    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:31032 RSC6    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:35999 RTC6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32030 RTK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34419 RTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36588 RTT107    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34611 RUD3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31985 RXT3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32185 SAC6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:32450 SAC7    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:36873 SAK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:31198 SAP155    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36905 BioGRID:33659 SAP185    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34018 SBA1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:33529 SCW4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34878 SDP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34908 SDS3    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:31439 SEC10    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33006 SEC15    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36739 SEC3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32871 SEC66    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31558 SEC72    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32420 SEM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34534 SFL1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36133 SGF11    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:30971 SGF29    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:34437 SHE4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31885 SHS1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:32011 SIT4    BioGRID  PubMed Affinity Capture-MS; Synthetic Lethality 
    BioGRID:36905 BioGRID:36152 SKS1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:32637 SKT5    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36461 SLT2    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:32041 SLX5    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:33323 SLX9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:33481 SMI1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:32561 SMT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34053 SMY1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:34712 SNC2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32529 SNF1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33136 SNF4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31232 SPA2    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:36905 BioGRID:36698 SPF1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33049 SPT16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35357 SPT21    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:31054 SRB8    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:34638 SRL1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36258 SRP54    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:35975 SRP72    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32345 SSD1    BioGRID  PubMed Dosage Rescue; Negative Genetic 
    BioGRID:36905 BioGRID:31279 SSK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32498 SSN2    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:36137 SSN3    BioGRID  PubMed Affinity Capture-MS; Positive Genetic 
    BioGRID:36905 BioGRID:35801 SSN8    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:35930 SSO1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36496 SSZ1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:33224 STT3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35211 SUB1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36987 SUS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36146 SVL3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34114 SWD2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33575 SWE1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33585 SWI3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36856 SWI4    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:32391 SWR1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:36263 SYT1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32895 TAF5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:33249 TFG2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36221 THP3    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33823 TOR1    BioGRID  PubMed Co-fractionation; Synthetic Lethality 
    BioGRID:36905 BioGRID:33920 TOR2    BioGRID  PubMed Co-fractionation; Negative Genetic 
    BioGRID:36905 BioGRID:35744 TPM1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36905 BioGRID:36838 TSC11    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:32039 TSC13    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31109 TUB2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:33322 TWF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:32786 UBC4    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:31941 UBP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:31160 UBP6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35401 UBP8    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34586 ULS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32267 UPC2    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36905 BioGRID:31645 VAC14    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:32298 VHS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31633 VID22    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33348 VMA21    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:33349 VOA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36061 VPS30    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:34152 VPS51    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31788 VPS8    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35717 YAF9    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:36568 YCK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:35675 YCK2    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:36449 YHR020W    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31469 YKE2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36905 BioGRID:36525 YNG2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36905 BioGRID:34315 YOL087C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36905 BioGRID:34637 YOR246C    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33046 YPT32    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:31529 YPT6    BioGRID  PubMed Negative Genetic 
    BioGRID:36905 BioGRID:33519 YTA7    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:35452 ZDS1    BioGRID  PubMed Positive Genetic 
    BioGRID:36905 BioGRID:34291 ZEO1    BioGRID  PubMed Negative Genetic 

    General gene information

    Homology

    Pathways from BioSystems

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Rho GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    actin cytoskeleton organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    PubMed 
    establishment of cell polarity TAS
    Traceable Author Statement
    more info
    PubMed 
    fungal-type cell wall organization TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of Rho protein signal transduction IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of Rho protein signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular bud tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    incipient cellular bud site IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    mating projection tip IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Names
    Bem2p
    NP_011082.1
    • Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3

      Range
      476345..482848, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179045.1NP_011082.1  Bem2p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P39960
      Conserved Domains (5) summary
      cd00155
      Location:588855
      Blast Score: 381
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      smart00324
      Location:19802161
      Blast Score: 403
      RhoGAP; GTPase-activator protein for Rho-like GTPases
      cl00273
      Location:18791948
      Blast Score: 100
      PH-like; Pleckstrin homology-like domain
      cl02520
      Location:11201291
      Blast Score: 140
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      cl02570
      Location:19652155
      Blast Score: 335
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006939.2 DAA07816.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39960.1 GenPept

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