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    MAG1 Mag1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856885, updated on 8-Jan-2012
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    Summary

    Gene symbol
    MAG1
    Gene description
    Mag1p
    Primary source
    SGD:S000000944
    Locus tag
    YER142C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MMS5
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    Genomic context

    Sequence :
    Chromosome: V; NC_001137.3 (455146..456036, complement)
    See MAG1 in MapViewer

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Cox15p Neighboring gene Ddi1p Neighboring gene Ubp5p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Histone H3 lysine 56 acetylation and the response to DNA replication fork damage. Wurtele H, et al. Mol Cell Biol, 2012 Jan. PMID 22025679.
    2. Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Fasolo J, et al. Genes Dev, 2011 Apr 1. PMID 21460040.
    3. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    4. The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent. Galli A, et al. J Biomed Biotechnol, 2009. PMID 19834566.
    5. The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1. Ma W, et al. Mol Cell Biol, 2009 Mar. PMID 19075004.

    See all (28) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36891 BioGRID:34785 AI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:36693 ANP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:34020 APN1    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Synthetic Rescue 
    BioGRID:36891 BioGRID:32679 APN2    BioGRID  PubMed Phenotypic Suppression; Synthetic Rescue 
    BioGRID:36891 BioGRID:31579 CDC3    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32219 CDC37    BioGRID  PubMed Positive Genetic 
    BioGRID:36891 BioGRID:31166 CMK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:36891 BioGRID:34387 CMK2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:36891 BioGRID:34859 CSM2    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:31730 FUN12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:36054 HHO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:32711 HHT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:32700 HTB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:36651 IMD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:31691 IMD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:35111 IMD4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:34692 ISW2    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:36038 KES1    BioGRID  PubMed Positive Genetic 
    BioGRID:36891 BioGRID:36337 MMS1    BioGRID  PubMed Phenotypic Enhancement; Positive Genetic 
    BioGRID:36891 BioGRID:33163 MMS2    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:34993 MPH1    BioGRID  PubMed Affinity Capture-MS; Negative Genetic; Phenotypic Enhancement 
    BioGRID:36891 BioGRID:34312 MSH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:34361 NOP12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:36594 PEX18    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:31960 POL3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36891 BioGRID:33794 POL32    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36891 BioGRID:31635 PSY3    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:36155 RAD1    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:35379 RAD14    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:31042 RAD18    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:33788 RAD26    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:34021 RAD27    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36891 BioGRID:32477 RAD30    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:31306 RAD5    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:35589 RAD50    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:36841 RAD51    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:35137 RAD52    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:33090 RAD54    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32131 RAD55    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32057 RAD57    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:31999 RAD59    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:33189 RAD6    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36891 BioGRID:32065 RAD61    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:34602 RET1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:34731 REV1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36891 BioGRID:36016 REV3    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:36891 BioGRID:36362 RPC82    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:36588 RTT107    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:31249 RTT109    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36891 BioGRID:32210 SAC3    BioGRID  PubMed Positive Genetic 
    BioGRID:36891 BioGRID:35368 SGS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:36420 SHU1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32133 SHU2    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:31404 SLX4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36891 BioGRID:31139 SMC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32211 SSY1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32926 SWC5    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:35325 SWP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:33139 TAF6    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:33414 TIF4631    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:33199 TIF4632    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:32511 TOM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:33333 UTP22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36891 BioGRID:31808 YAR029W    BioGRID  PubMed Negative Genetic 
    BioGRID:36891 BioGRID:32841 YBR141C    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    Pathways from BioSystems

    • Base excision repair, organism-specific biosystem (from KEGG)
      Base excision repair, organism-specific biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
    • Base excision repair, conserved biosystem (from KEGG)
      Base excision repair, conserved biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    alkylbase DNA N-glycosylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    alkylbase DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    DNA dealkylation involved in DNA repair IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    DNA dealkylation involved in DNA repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    DNA dealkylation involved in DNA repair ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    base-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    base-excision repair, AP site formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    base-excision repair, AP site formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Mag1p
    NP_011069.1
    • 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3

      Range
      455146..456036, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179032.1 → NP_011069.1  Mag1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P22134
      Conserved Domains (2) summary
      cd00056
      Location:84 – 234
      Blast Score: 172
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
      COG0122
      Location:2 – 291
      Blast Score: 430
      AlkA; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006939.2 DAA07803.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P22134.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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