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    SHO1 Sho1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856854, updated on 14-May-2013
    Gene symbol
    SHO1
    Gene description
    Sho1p
    Primary source
    SGD:S000000920
    Locus tag
    YER118C
    Gene type
    protein coding
    RNA name
    Sho1p
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SSU81
    Location :
    chromosome: V
    Sequence :
    Chromosome: V; NC_001137.3 (397952..399055, complement)
    See SHO1 in MapViewer

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene SUMO-targeted ubiquitin ligase complex subunit SLX8 Neighboring gene ribosomal 60S subunit protein L23B Neighboring gene Avt6p Neighboring gene Scs2p

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Proper protein glycosylation promotes mitogen-activated protein kinase signal fidelity. Lien EC, et al. Biochemistry, 2013 Jan 8. PMID 23210626.
    2. Sho1p connects the plasma membrane with proteins of the cytokinesis network through multiple isomeric interaction states. Labedzka K, et al. J Cell Sci, 2012 Sep 1. PMID 22623719.
    3. Multiplex assay for condition-dependent changes in protein-protein interactions. Schlecht U, et al. Proc Natl Acad Sci U S A, 2012 Jun 5. PMID 22615397.
    4. M-Track: detecting short-lived protein-protein interactions in vivo. Zuzuarregui A, et al. Nat Methods, 2012 Jun. PMID 22581371.
    5. Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Sharifpoor S, et al. Genome Res, 2012 Apr. PMID 22282571.

    See all (50) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Data showed that Msb2p had a function in cell polarization through the adaptor protein Sho1p that Hkr1p did not.
      Title: The signaling mucins Msb2 and Hkr1 differentially regulate the filamentation mitogen-activated protein kinase pathway and contribute to a multimodal response.
    2. Hkr1 and Msb2 individually form a complex with Sho1, and, upon high external osmolarity stress, appear to induce Sho1 to generate an intracellular signal
      Title: Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway.
    3. study showed that the membrane-bound osmosensor Sho1 is phosphorylated by Hog1 & that phosphorylation occurs on Ser-166; findings reveal a novel phosphorylation-dependent feedback loop leading to diminished cellular responses to an osmotic-stress stimulus
      Title: A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway.
    4. Sho1p plays role in signal transduction pathway.
      Title: Protein-protein interaction affinity plays a crucial role in controlling the Sho1p-mediated signal transduction pathway in yeast.
    Submit: New GeneRIF Correction
    Products Interactant Other Gene Complex Source Pubs Description
    NP_011043.1 NP_014378.1 ARK1    BIND  PubMed Ark1 weakly interacts with Sho1. In PMID 14668868, the authors describe this as a "putative physiologically relevant interaction". 
    NP_011043.1 NP_012407.1 PBS2    BIND  PubMed Sho1 interacts with Pbs2. 
    NP_011043.1 NP_011362.1 PEX14    BIND  PubMed Pex14 interacts with Sho1. In PMID 14668868, the authors describe this as a "putative physiologically relevant interaction". 
    NP_011043.1 NP_013466.1 STE11    BIND  PubMed Sho1 interacts with Ste11. 
    BioGRID:36863 BioGRID:35510 AAD14    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:32269 ADR1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:32891 AIM4    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36025 AIM44    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32320 AKR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32908 AME1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36693 ANP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:34639 APC5    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:34950 APQ12    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35524 ATP11    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36102 ATP4    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35722 AVT4    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:34160 BCH2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:30954 BIK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36930 BMH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36859 BOI2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31987 BRE1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36344 BSP1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31615 BUD8    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:36863 BioGRID:31825 CDC13    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36863 BioGRID:36600 CDC23    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31724 CDC24    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:36863 BioGRID:32620 CDC27    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31579 CDC3    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31066 CDC50    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33242 CDH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32726 CHS3    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:35540 CLA4    BioGRID  PubMed Dosage Growth Defect; Negative Genetic 
    BioGRID:36863 BioGRID:31085 COS4    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:33542 COS6    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:36377 COS8    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:34433 CRS5    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:34439 CYC2    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31945 CYK3    BioGRID  PubMed PCA; Reconstituted Complex; Two-hybrid 
    BioGRID:36863 BioGRID:33335 DBF2    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35713 DBP2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34699 DGK1    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:36576 DSE2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:32473 ERD1    BioGRID  PubMed Negative Genetic; PCA 
    BioGRID:36863 BioGRID:36894 FTR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:30956 FUS1    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:36863 BioGRID:31884 GCS1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36776 GLN3    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:33166 GUP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36863 BioGRID:32479 HKR1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:36863 BioGRID:35204 HOF1    BioGRID  PubMed PCA; Reconstituted Complex; Synthetic Lethality; Two-hybrid 
    BioGRID:36863 BioGRID:31384 HOG1    BioGRID  PubMed Biochemical Activity; Phenotypic Enhancement; Synthetic Lethality 
    BioGRID:36863 BioGRID:35881 HOL1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36423 HSE1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Growth Defect; Two-hybrid 
    BioGRID:36863 BioGRID:36774 HVG1    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:35677 INN1    BioGRID  PubMed PCA; Reconstituted Complex; Synthetic Growth Defect; Two-hybrid 
    BioGRID:36863 BioGRID:34293 INO4    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36752 ISC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35240 KAR5    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:33977 KDX1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33053 KEX1    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:31369 KIN2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:33041 KIP3    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:34576 LAS17    BioGRID  PubMed Protein-peptide; Two-hybrid 
    BioGRID:36863 BioGRID:33692 LAS21    BioGRID  PubMed PCA; Synthetic Lethality; Synthetic Rescue 
    BioGRID:36863 BioGRID:34536 LSC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33944 MCH2    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:33056 MCM6    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31595 MID2    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36863 BioGRID:32296 MNN10    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33579 MNN11    BioGRID  PubMed Negative Genetic; Phenotypic Suppression 
    BioGRID:36863 BioGRID:34583 MSB1    BioGRID  PubMed PCA; Reconstituted Complex 
    BioGRID:36863 BioGRID:33257 MSB2    BioGRID  PubMed Affinity Capture-Western; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36863 BioGRID:33509 MTM1    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:35285 MYO5    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:33430 PBP1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:33628 PBS2    BioGRID  PubMed Affinity Capture-Western; PCA; Reconstituted Complex; Synthetic Lethality; Two-hybrid 
    BioGRID:36863 BioGRID:35966 PCL8    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33303 PEF1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31026 PER1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:30975 PGS1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36863 BioGRID:32598 PKC1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34603 PTP2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34522 RGA1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36634 RPN10    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31152 RPN11    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31210 RPN12    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:34563 RPS28A    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:30952 RRP7    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31842 RTN2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:32210 SAC3    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:35255 SEC14    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34644 SEC63    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:32871 SEC66    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31558 SEC72    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:31762 SEO1    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:36863 SHO1    BioGRID  PubMed Affinity Capture-Western; PCA; Two-hybrid 
    BioGRID:36863 BioGRID:32692 SLA1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34845 SLN1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36863 BioGRID:34550 SLP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32041 SLX5    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32983 SNF5    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36210 SRO7    BioGRID  PubMed Negative Genetic; PCA 
    BioGRID:36863 BioGRID:31279 SSK1    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36863 BioGRID:35855 SSK2    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36863 BioGRID:31048 SSK22    BioGRID  PubMed Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36863 BioGRID:31710 SST2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31623 STE11    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:36863 BioGRID:36519 STE12    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36863 BioGRID:36419 STE20    BioGRID  PubMed Phenotypic Suppression; Two-hybrid 
    BioGRID:36863 BioGRID:30951 STE50    BioGRID  PubMed Negative Genetic; Reconstituted Complex 
    BioGRID:36863 BioGRID:31632 SUR4    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:32376 SWA2    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33585 SWI3    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:32200 SWI5    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35687 THO2    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34848 TID3    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36858 TMN3    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:33920 TOR2    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:31685 TUS1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:34836 UBP7    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36827 UTP7    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36717 VAC8    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:36214 VMA13    BioGRID  PubMed Synthetic Haploinsufficiency 
    BioGRID:36863 BioGRID:36702 VMA3    BioGRID  PubMed Synthetic Haploinsufficiency 
    BioGRID:36863 BioGRID:32136 VPS41    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35558 WSC2    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36863 BioGRID:31137 WWM1    BioGRID  PubMed Positive Genetic 
    BioGRID:36863 BioGRID:33080 XRN1    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:31267 YBT1    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:31988 YDL073W    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:36573 YHR140W    BioGRID  PubMed PCA 
    BioGRID:36863 BioGRID:33871 YJR115W    BioGRID  PubMed Two-hybrid 
    BioGRID:36863 BioGRID:35815 YNL010W    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:33531 YOR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36863 BioGRID:35170 YPT7    BioGRID  PubMed Negative Genetic 
    • MAPK Signaling Pathway, organism-specific biosystem (from WikiPathways)
      MAPK Signaling Pathway, organism-specific biosystemThe MAPK/ERK pathway is a signal transduction pathway that couples intracellular responses to the binding of growth factors to cell surface receptors. In many cell types, activation of this pathway p...
    • MAPK signaling pathway - yeast, organism-specific biosystem (from KEGG)
      MAPK signaling pathway - yeast, organism-specific biosystemThe S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third...
    • MAPK signaling pathway - yeast, conserved biosystem (from KEGG)
      MAPK signaling pathway - yeast, conserved biosystemThe S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third...

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    MAP-kinase scaffold activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    MAP-kinase scaffold activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    osmosensor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cellular response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    cytokinesis IGI
    Inferred from Genetic Interaction
    more info
    		  
    cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		  
    cytokinesis IPI
    Inferred from Physical Interaction
    more info
    		  
    establishment of cell polarity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    osmosensory signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    osmosensory signaling pathway IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    response to stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    signal transduction involved in filamentous growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    HICS complex IPI
    Inferred from Physical Interaction
    more info
    		  
    cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    cellular bud IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cellular bud IEA
    Inferred from Electronic Annotation
    more info
    		  
    cellular bud neck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cellular bud neck IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    mating projection tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane part IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Names
    Sho1p
    NP_011043.1
    • Transmembrane osmosensor involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3

      Range
      397952..399055, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179008.1 → NP_011043.1  Sho1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P40073
      Conserved Domains (1) summary
      cd11855
      Location:320 – 358
      Blast Score: 192
      SH3_Sho1p; Src homology 3 domain of High osmolarity signaling protein Sho1p
    Nucleotide Protein
    Heading Accession and Version
    genomic BK006939.2 DAA07778.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40073.1 GenPept

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • 3D structures
        3D structure of a gene
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • Taxonomy
        Link to related taxonomy entry

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