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    RTT107 Rtt107p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856559, updated on 21-Jan-2012

    Summary

    Gene symbol
    RTT107
    Gene description
    Rtt107p
    Primary source
    SGD:S000001197
    Locus tag
    YHR154W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ESC4

    Genomic context

    Sequence :
    Chromosome: VIII; NC_001140.6 (402966..406178)
    See RTT107 in MapViewer

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Spo12p Neighboring gene Spo16p Neighboring gene Ysp1p Neighboring gene ncRNA

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36588 BioGRID:36831 AIM10    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36588 BioGRID:32891 AIM4    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34020 APN1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36562 ARP1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36588 BioGRID:34535 ARP8    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33639 ASF1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36905 BEM2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31987 BRE1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36588 BioGRID:31745 CCR4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35210 CCS1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:30980 CDC10    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31937 CDC48    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:32038 CDC7    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33242 CDH1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35540 CLA4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36287 CLB2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31058 CSM1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:34859 CSM2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:35222 CSM3    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:35254 CTF18    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36302 CTF4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36625 CTF8    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:34272 CTR9    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:32106 DBF4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32025 DBP10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:30968 DCC1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:34699 DGK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34479 DIA2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36588 BioGRID:32496 DOT1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36588 BioGRID:33667 DPB11    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:36588 BioGRID:33205 DST1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31961 DUN1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32415 EAF1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:34541 ELG1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35743 EOS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34635 ESA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32418 ESC2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34353 GAL11    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33985 GPM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:32479 HKR1    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:34428 HST3    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36588 BioGRID:32244 HST4    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36588 BioGRID:33086 HUR1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:31643 IKI3    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:35207 IMP2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32127 IPT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:36773 KRE29    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:36588 BioGRID:31742 LTE1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36891 MAG1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31554 MEC3    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:36337 MMS1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36711 MMS21    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:36588 BioGRID:31584 MMS22    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Growth Defect; Two-hybrid 
    BioGRID:36588 BioGRID:32804 MMS4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35016 MND2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:35541 MON2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36588 BioGRID:33758 MPP10    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:35402 MRE11    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36553 MSH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:32447 MUS81    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36227 NHP6A    BioGRID  PubMed PCA 
    BioGRID:36588 BioGRID:32795 NHP6B    BioGRID  PubMed PCA; Reconstituted Complex 
    BioGRID:36588 BioGRID:32489 NPL3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:31280 NSE1    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:32341 NSE3    BioGRID  PubMed Phenotypic Enhancement; Two-hybrid 
    BioGRID:36588 BioGRID:31957 NSE4    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:35146 NSE5    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Phenotypic Enhancement; Synthetic Growth Defect; Two-hybrid 
    BioGRID:36588 BioGRID:31790 NUP60    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31946 NUP84    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:33102 NUT1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31417 PEP3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33087 PMR1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32794 POL30    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:35877 POP2    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36588 BioGRID:31635 PSY3    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31238 PUF3    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:36155 RAD1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36588 BioGRID:35379 RAD14    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36588 BioGRID:31042 RAD18    BioGRID  PubMed Phenotypic Enhancement; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36692 RAD23    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:36926 RAD24    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:36588 BioGRID:34021 RAD27    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35589 RAD50    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36588 BioGRID:36841 RAD51    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35137 RAD52    BioGRID  PubMed Phenotypic Enhancement; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33090 RAD54    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32131 RAD55    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Two-hybrid 
    BioGRID:36588 BioGRID:32057 RAD57    BioGRID  PubMed Affinity Capture-Western; Negative Genetic 
    BioGRID:36588 BioGRID:31999 RAD59    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33189 RAD6    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32270 RAD9    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:36588 BioGRID:32751 REB1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:32962 REI1    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:34731 REV1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36016 REV3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32191 RGP1    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:31923 RGT2    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:36153 RMI1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36679 RML2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31631 ROM2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34724 RPA190    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:36634 RPN10    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:31210 RPN12    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31965 RPN6    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31602 RPP0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:31980 RPP1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:34363 RPP2A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:36408 RPS20    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:36817 RPS24A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:36462 RRM3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36588 BioGRID:33708 RTT101    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36588 RTT107    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:31922 SCM3    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:35368 SGS1    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement; Synthetic Growth Defect; Synthetic Lethality; Two-hybrid 
    BioGRID:36588 BioGRID:36842 SHC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:36420 SHU1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:32133 SHU2    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:31701 SIR3    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:32279 SIR4    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:32923 SLX1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:36588 BioGRID:31404 SLX4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid 
    BioGRID:36588 BioGRID:32041 SLX5    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:36861 SLX8    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:34366 SMC5    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:36588 BioGRID:31642 SMC6    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Negative Genetic; Phenotypic Enhancement; Two-hybrid 
    BioGRID:36588 BioGRID:33860 SOD1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:33308 SPT4    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34223 SRP40    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:33665 SRS2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36588 BioGRID:31786 SSA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:31882 SSB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:35801 SSN8    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36588 BioGRID:30973 STP22    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:31453 SWI6    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36588 BioGRID:36052 TAF14    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:31037 TAH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:33445 TDH3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:32820 TEF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:32616 TEL1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35567 TOF1    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:34398 TOP1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:31503 TOP3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35331 TPP1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:35141 TSA1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:31633 VID22    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:34016 VPH2    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:36567 WSS1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36588 BioGRID:32428 XRS2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36588 BioGRID:36993 YBR296C-A    BioGRID  PubMed PCA 
    BioGRID:36588 BioGRID:34155 YKR023W    BioGRID  PubMed Two-hybrid 
    BioGRID:36588 BioGRID:35085 YML119W    BioGRID  PubMed Positive Genetic 
    BioGRID:36588 BioGRID:35674 YNL155W    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36588 BioGRID:35873 YNR048W    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:34721 YOR338W    BioGRID  PubMed Negative Genetic 
    BioGRID:36588 BioGRID:33698 ZAP1    BioGRID  PubMed Synthetic Growth Defect 

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    double-strand break repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transposition, RNA-mediated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Cul8-RING ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
     
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Names
    Rtt107p
    NP_012024.1
    • Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6

      Range
      402966..406178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179285.1NP_012024.1  Rtt107p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P38850
      Conserved Domains (1) summary
      cl00038
      Location:380448
      Blast Score: 165
      BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006934.2 DAA06847.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P38850.1 GenPept

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