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KSP1 Ksp1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 856482, updated on 14-Sep-2014
Gene symbol
KSP1
Gene description
Ksp1p
Primary source
SGD:S000001124
Locus tag
YHR082C
Gene type
protein coding
RNA name
Ksp1p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See KSP1 in MapViewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (268459..271548, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Lrp1p Neighboring gene Sam35p Neighboring gene Ste12p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
mRNA binding IDA
Inferred from Direct Assay
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity ISA
Inferred from Sequence Alignment
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
TOR signaling IMP
Inferred from Mutant Phenotype
more info
 
TOR signaling IPI
Inferred from Physical Interaction
more info
 
cellular protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of macroautophagy IGI
Inferred from Genetic Interaction
more info
 
negative regulation of macroautophagy IMP
Inferred from Mutant Phenotype
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation ISA
Inferred from Sequence Alignment
more info
PubMed 
regulation of filamentous growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Ksp1p
NP_011950.1
  • Serine/threonine protein kinase; associates with TORC1 and likely involved in TOR signaling cascades; negative regulator of autophagy; nuclear translocation required for haploid filamentous growth; regulates filamentous growth induced nuclear translocation of Bcy1p, Fus3p, and Sks1p; overproduction causes allele-specific suppression of prp20-10; protein abundance increases in response to DNA replication stress

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 

    Range
    268459..271548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179212.1NP_011950.1  Ksp1p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_011950.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P38691
    Conserved Domains (2) summary
    cd00180
    Location:118282
    Blast Score: 368
    PKc; Catalytic domain of Protein Kinases
    smart00220
    Location:18335
    Blast Score: 420
    S_TKc; Serine/Threonine protein kinases, catalytic domain