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    CPR2 Cpr2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856454, updated on 4-Feb-2012
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    Summary

    Gene symbol
    CPR2
    Gene description
    Cpr2p
    Primary source
    SGD:S000001099
    Locus tag
    YHR057C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CYP2
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    Genomic context

    Sequence :
    Chromosome: VIII; NC_001140.6 (218226..218843, complement)
    See CPR2 in MapViewer

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cup1-2p Neighboring gene Rsc30p Neighboring gene Med6p Neighboring gene Fyv4p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Scherrer T, et al. Genome Biol, 2011. PMID 21232131.
    2. A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. Finnigan GC, et al. Genetics, 2011 Mar. PMID 21196517.
    3. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    4. Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. Batisse J, et al. J Biol Chem, 2009 Dec 11. PMID 19840948.
    5. High-quality binary protein interaction map of the yeast interactome network. Yu H, et al. Science, 2008 Oct 3. PMID 18719252.

    See all (10) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36489 BioGRID:36225 ATG11    BioGRID  PubMed Negative Genetic 
    BioGRID:36489 BioGRID:31351 BOS1    BioGRID  PubMed Positive Genetic 
    BioGRID:36489 BioGRID:34429 BUB3    BioGRID  PubMed Negative Genetic 
    BioGRID:36489 BioGRID:32907 ERV15    BioGRID  PubMed Negative Genetic 
    BioGRID:36489 BioGRID:31962 GET3    BioGRID  PubMed Two-hybrid 
    BioGRID:36489 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36489 BioGRID:33845 JSN1    BioGRID  PubMed Two-hybrid 
    BioGRID:36489 BioGRID:31756 MDM10    BioGRID  PubMed Negative Genetic 
    BioGRID:36489 BioGRID:34074 MPE1    BioGRID  PubMed Negative Genetic 
    BioGRID:36489 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36489 BioGRID:34213 NUP133    BioGRID  PubMed Positive Genetic 
    BioGRID:36489 BioGRID:36035 PPT2    BioGRID  PubMed Negative Genetic 
    BioGRID:36489 BioGRID:33348 VMA21    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36489 BioGRID:33349 VOA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36489 BioGRID:31565 YLR301W    BioGRID  PubMed Negative Genetic 
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    General gene information

    Homology

    • Homologs of the CPR2 gene: The CPR2 gene is conserved in human, dog, cow, mouse, rat, chicken, zebrafish, S.cerevisiae, and A.thaliana.

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    peptide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    peptidyl-prolyl cis-trans isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
    		  
    protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
    		  
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Cpr2p
    NP_011924.1
    • Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6

      Range
      218226..218843, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179187.1 → NP_011924.1  Cpr2p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P23285
      Conserved Domains (2) summary
      PRK10791
      Location:50 – 195
      Blast Score: 132
      PRK10791; peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional
      cl00197
      Location:37 – 197
      Blast Score: 525
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006934.2 DAA06750.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P23285.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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