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    VMA16 Vma16p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856421, updated on 5-Feb-2012
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    Summary

    Gene symbol
    VMA16
    Gene description
    Vma16p
    Primary source
    SGD:S000001068
    Locus tag
    YHR026W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PPA1
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    Genomic context

    Sequence :
    Chromosome: VIII; NC_001140.6 (160844..161485)
    See VMA16 in MapViewer

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Mas2p Neighboring gene Thr1p Neighboring gene Rpn1p Neighboring gene Dap2p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. León Ortiz AM, et al. DNA Repair (Amst), 2011 May 5. PMID 21459050.
    2. Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Scherrer T, et al. Genome Biol, 2011. PMID 21232131.
    3. Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae. Libuda DE, et al. Genetics, 2010 Apr. PMID 20139344.
    4. A different conformation for EGC stator subcomplex in solution and in the assembled yeast V-ATPase: possible implications for regulatory disassembly. Diepholz M, et al. Structure, 2008 Dec 10. PMID 19081055.
    5. Voa1p functions in V-ATPase assembly in the yeast endoplasmic reticulum. Ryan M, et al. Mol Biol Cell, 2008 Dec. PMID 18799613.

    See all (22) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Subunit c'' of the vacuolar H+-ATPase (V-ATPase) is not essential for assembly of the V-ATPase complex but is required for the functional coupling of the two domains of V-ATPase.
      Title: Assembly of the yeast vacuolar H+-ATPase and ATP hydrolysis occurs in the absence of subunit c''.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36457 BioGRID:30959 AGP1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:32814 ALG1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:36440 ARD1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36457 BioGRID:34905 AVT7    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33931 CNB1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36457 BioGRID:35073 COS3    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:36377 COS8    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:32737 CSG2    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:34490 ECM3    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:31759 ERP2    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:34420 ERP4    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33534 ERV29    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:35487 GAS1    BioGRID  PubMed Dosage Rescue 
    BioGRID:36457 BioGRID:33226 GET1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36457 BioGRID:36828 GET2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36457 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36457 BioGRID:32388 GPI8    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:35029 GTT1    BioGRID  PubMed Two-hybrid 
    BioGRID:36457 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36457 BioGRID:32277 HTA1    BioGRID  PubMed Negative Genetic 
    BioGRID:36457 BioGRID:32276 HTB1    BioGRID  PubMed Negative Genetic 
    BioGRID:36457 BioGRID:32858 IFA38    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33845 JSN1    BioGRID  PubMed Two-hybrid 
    BioGRID:36457 BioGRID:35601 KEX2    BioGRID  PubMed Dosage Rescue 
    BioGRID:36457 BioGRID:32005 MCH1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33944 MCH2    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:32018 NAT1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36457 BioGRID:31879 OST4    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:30933 PBN1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:32810 PHO88    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:36744 PRE1    BioGRID  PubMed Dosage Lethality 
    BioGRID:36457 BioGRID:31208 PRE4    BioGRID  PubMed Dosage Lethality 
    BioGRID:36457 BioGRID:33189 RAD6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36457 BioGRID:36368 SGE1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:31833 SHR3    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:31308 SMF3    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33665 SRS2    BioGRID  PubMed Dosage Lethality 
    BioGRID:36457 BioGRID:31632 SUR4    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:35325 SWP1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33511 TNA1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:31224 TPO1    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:36323 TPO3    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:32039 TSC13    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:35928 VMA11    BioGRID  PubMed Co-fractionation 
    BioGRID:36457 BioGRID:36457 VMA16    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:33348 VMA21    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36457 BioGRID:36702 VMA3    BioGRID  PubMed Affinity Capture-Western; PCA 
    BioGRID:36457 BioGRID:34659 VPH1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:36457 BioGRID:31748 YAL018C    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:31807 YAR028W    BioGRID  PubMed PCA 
    BioGRID:36457 BioGRID:34068 YET1    BioGRID  PubMed PCA 
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    General gene information

    Homology

    • Homologs of the VMA16 gene: The VMA16 gene is conserved in human, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice, and P.falciparum.

    Pathways from BioSystems

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    hydrogen ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    proton-transporting ATPase activity, rotational mechanism TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    ATP hydrolysis coupled proton transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    proton transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    vacuolar acidification TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    integral to membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    proton-transporting V-type ATPase, V0 domain IEA
    Inferred from Electronic Annotation
    more info
    		  
    proton-transporting two-sector ATPase complex, proton-transporting domain IEA
    Inferred from Electronic Annotation
    more info
    		  
    vacuolar proton-transporting V-type ATPase, V0 domain TAS
    Traceable Author Statement
    more info
    		 PubMed 
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    General protein information

    Names
    Vma16p
    NP_011891.1
    • Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6

      Range
      160844..161485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179156.1 → NP_011891.1  Vma16p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P23968
      Conserved Domains (1) summary
      cl00466
      Location:59 – 124
      Blast Score: 155
      ATP-synt_C; ATP synthase subunit C
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006934.2 DAA06717.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P23968.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content