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SNF6 Snf6p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856360, updated on 13-Apr-2024

Summary

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Gene symbol
SNF6
Gene description
Snf6p
Primary source
SGD:S000001017
Locus tag
YHL025W
See related
AllianceGenome:SGD:S000001017
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables rDNA binding activity. Involved in chromatin remodeling; nucleic acid metabolic process; and positive regulation of transcription, DNA-templated. Located in cytosol and nucleus. Part of SWI/SNF complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (54851..55849)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene alkaline-responsive transcriptional regulator RIM101 Neighboring gene uncharacterized protein Neighboring gene Rim4p Neighboring gene Npr3p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Detection of an altered heterochromatin structure in the absence of the nucleotide excision repair protein Rad4 in Saccharomyces cerevisiae. Zhang L, et al. Cell Cycle, 2013 Aug 1. PMID 23839037, Free PMC Article
  2. SNF6 encodes a nuclear protein that is required for expression of many genes in Saccharomyces cerevisiae. Estruch F, et al. Mol Cell Biol, 1990 Jun. PMID 2188093, Free PMC Article
  3. The SNF2, SNF5 and SNF6 genes are required for Ty transcription in Saccharomyces cerevisiae. Happel AM, et al. Genetics, 1991 May. PMID 1648006, Free PMC Article
  4. SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes. Nikolov VN, et al. Nat Commun, 2022 Apr 12. PMID 35413952, Free PMC Article
  5. Assays for chromatin remodeling during nucleotide excision repair in Saccharomyces cerevisiae. Zhang L, et al. Methods, 2009 May. PMID 19336254, Free PMC Article

See all (140) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structure of the yeast Swi/Snf complex in a nucleosome free state.
    Title: Structure of the yeast Swi/Snf complex in a nucleosome free state.
  2. These results indicate that the SWI/SNF chromatin-remodeling complex is recruited to DNA lesions by damage-recognition proteins to increase DNA accessibility for NER in chromatin.
    Title: Rad4-Rad23 interaction with SWI/SNF links ATP-dependent chromatin remodeling with nucleotide excision repair.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables rDNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in chromatin remodeling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in maturation of LSU-rRNA IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleotide-excision repair IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SWI/SNF complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SWI/SNF complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Snf6p
NP_011838.1
  • Subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; relocates to the cytosol under hypoxic conditions

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    54851..55849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179105.1 → NP_011838.1  TPA: Snf6p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011838.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKU3, P18888
    UniProtKB/TrEMBL
    A0A6A5PX02, A6ZSM6, B3LS94, C7GIR1, C8ZA39, G2WF41, N1P160
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
7C4J_C.1
P18888.1

Gene LinkOut

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