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HDA3 Hda3p [ Saccharomyces cerevisiae S288c ]

Gene ID: 856309, updated on 12-Jul-2016
Gene symbol
HDA3
Gene description
Hda3p
Primary source
SGD:S000006383
Locus tag
YPR179C
Gene type
protein coding
RNA name
Hda3p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PLO1
See HDA3 in Map Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (893797..895764, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Rab geranylgeranyltransferase BET2 Neighboring gene U4/U6-U5 snRNP complex subunit PRP4 Neighboring gene E1 ubiquitin-activating protein AOS1 Neighboring gene GTPase-activating protein SEC23

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to histone deacetylase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
covalent chromatin modification IEA
Inferred from Electronic Annotation
more info
 
gene silencing by RNA IMP
Inferred from Mutant Phenotype
more info
PubMed 
gene silencing involved in chronological cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
histone deacetylation IDA
Inferred from Direct Assay
more info
PubMed 
histone deacetylation IEA
Inferred from Electronic Annotation
more info
 
histone deacetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
HDA1 complex IDA
Inferred from Direct Assay
more info
PubMed 
HDA1 complex IEA
Inferred from Electronic Annotation
more info
 
HDA1 complex IPI
Inferred from Physical Interaction
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Hda3p
NP_015505.1
  • Subunit of the HDA1 histone deacetylase complex; possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; relocalizes to the cytosol in response to hypoxia; similar to Hda2p

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    893797..895764 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184276.1NP_015505.1  Hda3p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_015505.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q06623
    Conserved Domains (2) summary
    pfam11496
    Location:26299
    HDA2-3; Class II histone deacetylase complex subunits 2 and 3
    cl22438
    Location:530634
    TMF_TATA_bd; TATA element modulatory factor 1 TATA binding