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    MMS1 Mms1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856293, updated on 5-May-2013
    Gene symbol
    MMS1
    Gene description
    Mms1p
    Primary source
    SGD:S000006368
    Locus tag
    YPR164W
    Gene type
    protein coding
    RNA name
    Mms1p
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RTT108; SLM6
    Location :
    chromosome: XVI
    Sequence :
    Chromosome: XVI; NC_001148.4 (870703..874926)
    See MMS1 in MapViewer

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene origin recognition complex subunit 4 Neighboring gene Tif3p Neighboring gene Rho1p Neighboring gene mitochondrial 37S ribosomal protein MRP2

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36337 BioGRID:31400 ACE2    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31107 ACT1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34535 ARP8    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33639 ASF1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33807 BFA1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:36749 BIM1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36337 BioGRID:31987 BRE1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35231 BUB2    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34429 BUB3    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31745 CCR4    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36337 BioGRID:35210 CCS1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:31825 CDC13    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32107 CDC34    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36337 BioGRID:33569 CDC6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36337 BioGRID:31676 CDC73    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35376 CIK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35540 CLA4    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36287 CLB2    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33472 CRM1    BioGRID  PubMed Two-hybrid 
    BioGRID:36337 BioGRID:31058 CSM1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35254 CTF18    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:36302 CTF4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:36337 BioGRID:36625 CTF8    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:34479 DIA2    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36598 DNA2    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36337 BioGRID:33952 DOA1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33205 DST1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34185 DYN1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32415 EAF1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:34085 ELM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34635 ESA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32418 ESC2    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:36337 BioGRID:31502 EST1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:34435 EXO1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33226 GET1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32711 HHT1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36337 BioGRID:32227 HMO1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33895 HOM6    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34242 HRT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36337 BioGRID:34032 HSL1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34428 HST3    BioGRID  PubMed Positive Genetic; Synthetic Rescue 
    BioGRID:36337 BioGRID:32244 HST4    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36337 BioGRID:34392 HTZ1    BioGRID  PubMed Positive Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33086 HUR1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33874 ILM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34293 INO4    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:31196 IRC5    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32067 KCS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32550 LCD1    BioGRID  PubMed Dosage Growth Defect 
    BioGRID:36337 BioGRID:32495 LRS4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33632 LSM1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32437 LSM6    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35681 LSM7    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33962 LST4    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31742 LTE1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36891 MAG1    BioGRID  PubMed Phenotypic Enhancement; Positive Genetic 
    BioGRID:36337 BioGRID:34863 MET18    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35208 MIH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31584 MMS22    BioGRID  PubMed Affinity Capture-Western; Positive Genetic 
    BioGRID:36337 BioGRID:32804 MMS4    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32296 MNN10    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:30926 MRC1    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:35402 MRE11    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35077 MSC1    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:32489 NPL3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:34604 NPT1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:31946 NUP84    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32764 ORC2    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35578 ORC5    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:36337 BioGRID:36551 ORC6    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36337 BioGRID:31052 PAT1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33087 PMR1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35741 PMS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35097 POB3    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36337 BioGRID:31960 POL3    BioGRID  PubMed Negative Genetic; Phenotypic Enhancement 
    BioGRID:36337 BioGRID:32794 POL30    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33794 POL32    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:35877 POP2    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36337 BioGRID:35766 POR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36337 BioGRID:32130 PPH3    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32491 PPM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32556 PSP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35633 PSY2    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32048 PTC1    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:31042 RAD18    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36926 RAD24    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:36337 BioGRID:34021 RAD27    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36915 RAD4    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:36337 BioGRID:35589 RAD50    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36841 RAD51    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35137 RAD52    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:36030 RAD53    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33090 RAD54    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32131 RAD55    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32057 RAD57    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:31999 RAD59    BioGRID  PubMed Phenotypic Enhancement; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33189 RAD6    BioGRID  PubMed Phenotypic Enhancement; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32270 RAD9    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:36337 BioGRID:35629 RIO2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36337 BioGRID:36153 RMI1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32332 RNH202    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35678 RPC31    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:36462 RRM3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:36337 BioGRID:34419 RTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33708 RTT101    BioGRID  PubMed Affinity Capture-Western; Positive Genetic 
    BioGRID:36337 BioGRID:36850 RTT105    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:36588 RTT107    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33953 SAC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31198 SAP155    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35304 SAS2    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:35451 SCS7    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35255 SEC14    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35368 SGS1    BioGRID  PubMed Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:32641 SHP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:36640 SKN7    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:31404 SLX4    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32041 SLX5    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:36861 SLX8    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32561 SMT3    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33860 SOD1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:36337 BioGRID:36299 SPN1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33049 SPT16    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36337 BioGRID:33308 SPT4    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33665 SRS2    BioGRID  PubMed Dosage Lethality; Negative Genetic; Synthetic Growth Defect; Synthetic Lethality; Two-hybrid 
    BioGRID:36337 BioGRID:36987 SUS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32926 SWC5    BioGRID  PubMed Positive Genetic 
    BioGRID:36337 BioGRID:36856 SWI4    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31453 SWI6    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33765 TDH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36337 BioGRID:34329 THP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:34398 TOP1    BioGRID  PubMed Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35141 TSA1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33436 UBR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32873 UMP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:33348 VMA21    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:33349 VOA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36337 BioGRID:34487 VPS21    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:31788 VPS8    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:32428 XRS2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:35163 YAP1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:36337 BioGRID:31796 YAR010C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36337 BioGRID:34063 YKL069W    BioGRID  PubMed Negative Genetic 
    BioGRID:36337 BioGRID:35017 YVH1    BioGRID  PubMed Affinity Capture-MS 

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of transposition, RNA-mediated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nonfunctional rRNA decay IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    recombinational repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    replication fork processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Cul8-RING ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Mms1p
    NP_015490.1
    • Subunit of an E3 ubiquitin ligase complex involved in replication repair; stabilizes protein components of the replication fork such as the fork-pausing complex and leading strand polymerase, preventing fork collapse and promoting efficient recovery during replication stress; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4

      Range
      870703..874926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184261.1NP_015490.1  Mms1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q06211
      Conserved Domains (1) summary
      pfam10433
      Location:154677
      Blast Score: 539
      MMS1_N; Mono-functional DNA-alkylating methyl methanesulfonate N-term

      Supplemental Content

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