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    RPC40 Rpc40p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856226, updated on 31-Jan-2012
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    Summary

    Gene symbol
    RPC40
    Gene description
    Rpc40p
    Primary source
    SGD:S000006314
    Locus tag
    YPR110C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPC5
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    Genomic context

    Sequence :
    Chromosome: XVI; NC_001148.4 (745828..746835, complement)
    See RPC40 in MapViewer

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene tRNA Neighboring gene hypothetical protein Neighboring gene Dbf20p Neighboring gene Mrd1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae. García-Gómez JJ, et al. Mol Cell Biol, 2011 Oct. PMID 21825077.
    2. Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Lee KK, et al. Mol Syst Biol, 2011 Jul 5. PMID 21734642.
    3. Perinuclear cohibin complexes maintain replicative life span via roles at distinct silent chromatin domains. Chan JN, et al. Dev Cell, 2011 Jun 14. PMID 21664583.
    4. Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells. Schwer B, et al. Nucleic Acids Res, 2011 Aug. PMID 21558325.
    5. A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis. Ziv I, et al. Mol Cell Proteomics, 2011 May. PMID 21427232.

    See all (43) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36277 BioGRID:35841 ACC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32683 ACH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35483 ADH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32269 ADR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32268 AHA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31055 AHC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33098 AMS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31853 ARF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31924 ARF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32944 ARO4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36225 ATG11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36749 BIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:35876 BRE5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34429 BUB3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33079 BUD13    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:31446 CBF5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31499 CDC42    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36277 BioGRID:36023 CDC60    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34955 CKA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34441 CKB2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31908 CLB3    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:36277 BioGRID:34084 CSE4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35222 CSM3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:30968 DCC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31903 DHH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34381 DIS3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32195 DOP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35002 DSN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36392 ECM29    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35186 ERG5    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:31505 FAR10    BioGRID  PubMed Two-hybrid 
    BioGRID:36277 BioGRID:31747 FUN30    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:35915 GAL4    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:36759 GCD11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33503 GCN5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35635 GCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34030 GFA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36277 BioGRID:36616 GND1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32995 GUS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32710 HHF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31883 HO    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:36240 HOS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32699 HTA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31003 HTL1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34531 IDH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32626 ILS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36239 ISA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32940 ISW1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33230 KAP122    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35944 KAR9    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:33080 KEM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35601 KEX2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:35531 KRI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32495 LRS4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33632 LSM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33164 MAD1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32058 MAF1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:36277 BioGRID:35532 MCK1    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:34048 MDH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34863 MET18    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35104 MFT1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:35541 MON2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34312 MSH2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:35703 NAF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34179 NAP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33680 NET1    BioGRID  PubMed PCA 
    BioGRID:36277 BioGRID:35465 NGL2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36227 NHP6A    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34698 NOP58    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31751 NTG1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35101 ORC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36737 PAC2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31927 PPH21    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32130 PPH3    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:33383 PRE9    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34349 PSH1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33185 PYC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32915 PYC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34021 RAD27    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32057 RAD57    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32065 RAD61    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33096 RCK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32751 REB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34602 RET1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32970 RIF1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33820 RPA12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36188 RPA135    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:36277 BioGRID:32208 RPA14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34724 RPA190    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; PCA 
    BioGRID:36277 BioGRID:33610 RPA34    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:36277 BioGRID:34723 RPA43    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:36277 BioGRID:35591 RPA49    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34605 RPB10    BioGRID  PubMed Affinity Capture-MS; Dosage Rescue 
    BioGRID:36277 BioGRID:32853 RPB5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34618 RPB8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36577 RPC10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33744 RPC17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35712 RPC19    BioGRID  PubMed Affinity Capture-MS; Dosage Rescue; PCA; Two-hybrid 
    BioGRID:36277 BioGRID:33992 RPC25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35678 RPC31    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35829 RPC34    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34157 RPC37    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36277 RPC40    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31911 RPC53    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36362 RPC82    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31152 RPN11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36755 RPN3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32035 RPN4    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:36359 RPO26    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34512 RPO31    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36462 RRM3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34404 RRP6    BioGRID  PubMed Affinity Capture-MS; Negative Genetic 
    BioGRID:36277 BioGRID:34419 RTS1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31249 RTT109    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32449 RVS167    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33006 SEC15    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36277 BioGRID:32782 SEC18    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36277 BioGRID:33115 SEC27    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33461 SER2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:30971 SGF29    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32641 SHP1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31352 SIC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31404 SLX4    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:31359 SMC4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32561 SMT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:33136 SNF4    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31147 SPB4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35159 SPT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32783 SPT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36210 SRO7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34223 SRP40    BioGRID  PubMed Dosage Rescue 
    BioGRID:36277 BioGRID:33947 SRY1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31882 SSB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:35627 SSB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36123 SUR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31755 SWC3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33585 SWI3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32849 TBS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36601 THP2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33434 TIM13    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:34143 TOF2    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:31503 TOP3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:33221 TRP5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32508 TSA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36238 UBA3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32149 UBC13    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:36719 UBC8    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31215 UBI4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34519 UBP2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:36901 UBP3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31160 UBP6    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32257 UME6    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:35609 URE2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34502 VAM3    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:31859 VMA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:34716 VMA4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32546 VPS3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:32251 VPS64    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:35128 VPS71    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:34444 WHI2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:32428 XRS2    BioGRID  PubMed Negative Genetic 
    BioGRID:36277 BioGRID:36885 YER138C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31104 YFL042C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:36545 YHR112C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36277 BioGRID:31469 YKE2    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:35281 YKU80    BioGRID  PubMed Positive Genetic 
    BioGRID:36277 BioGRID:33519 YTA7    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the RPC40 gene: The RPC40 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, and rice.

    Pathways from BioSystems

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to DNA-directed RNA polymerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    DNA-directed RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    tRNA transcription from RNA polymerase III promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    transcription from RNA polymerase I promoter IC
    Inferred by Curator
    more info
    		 PubMed 
    transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    DNA-directed RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    DNA-directed RNA polymerase III complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Rpc40p
    NP_015435.1
    • RNA polymerase subunit AC40, common to RNA polymerase I and III
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4

      Range
      745828..746835, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184207.1 → NP_015435.1  Rpc40p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P07703
      Conserved Domains (2) summary
      cd07032
      Location:40 – 330
      Blast Score: 1244
      RNAP_I_II_AC40; AC40 subunit of Eukaryotic RNA polymerase (RNAP) I and RNAP III
      smart00662
      Location:52 – 329
      Blast Score: 649
      RPOLD; RNA polymerases D
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006949.2 DAA11525.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P07703.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content