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    TIP41 Tip41p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856153, updated on 6-Feb-2012
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    Summary

    Gene symbol
    TIP41
    Gene description
    Tip41p
    Primary source
    SGD:S000006244
    Locus tag
    YPR040W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: XVI; NC_001148.4 (647305..648375)
    See TIP41 in MapViewer

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Erv2p Neighboring gene Tif5p Neighboring gene Puf2p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. Stirling PC, et al. PLoS Genet, 2011 Apr. PMID 21552543.
    2. New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1. Cocklin R, et al. Genetics, 2011 Mar. PMID 21196523.
    3. A global protein kinase and phosphatase interaction network in yeast. Breitkreutz A, et al. Science, 2010 May 21. PMID 20489023.
    4. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    5. Normal function of the yeast TOR pathway requires the type 2C protein phosphatase Ptc1. González A, et al. Mol Cell Biol, 2009 May. PMID 19273591.

    See all (25) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:36217 BioGRID:36256 ASA1    BioGRID  PubMed Synthetic Rescue 
    BioGRID:36217 BioGRID:34957 BCY1    BioGRID  PubMed PCA 
    BioGRID:36217 BioGRID:36749 BIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:35569 BNI1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36217 BioGRID:35876 BRE5    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:33832 CDC11    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:32107 CDC34    BioGRID  PubMed Synthetic Lethality 
    BioGRID:36217 BioGRID:34479 DIA2    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:32780 ECM33    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:36217 BioGRID:33086 HUR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:32368 IPK1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:31947 IWR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:36620 KOG1    BioGRID  PubMed Dosage Rescue 
    BioGRID:36217 BioGRID:34719 KRE5    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:35077 MSC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:32213 NBP2    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:35573 PIK1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:36217 BioGRID:33087 PMR1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:35097 POB3    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:32662 POL12    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:35856 PPG1    BioGRID  PubMed Two-hybrid 
    BioGRID:36217 BioGRID:31927 PPH21    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:36217 BioGRID:31857 PPH22    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:36217 BioGRID:32130 PPH3    BioGRID  PubMed Two-hybrid 
    BioGRID:36217 BioGRID:35633 PSY2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36217 BioGRID:32651 PSY4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36217 BioGRID:32048 PTC1    BioGRID  PubMed Negative Genetic 
    BioGRID:36217 BioGRID:36623 PTH1    BioGRID  PubMed Positive Genetic 
    BioGRID:36217 BioGRID:33816 PTK2    BioGRID  PubMed Biochemical Activity 
    BioGRID:36217 BioGRID:36679 RML2    BioGRID  PubMed Positive Genetic 
    BioGRID:36217 BioGRID:31914 RPN5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36217 BioGRID:32485 RPN9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36217 BioGRID:31198 SAP155    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; PCA; Synthetic Rescue 
    BioGRID:36217 BioGRID:33659 SAP185    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:36217 BioGRID:33010 SAP4    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:36217 BioGRID:35200 TAP42    BioGRID  PubMed Affinity Capture-Western; Phenotypic Suppression; Synthetic Growth Defect; Synthetic Rescue; Two-hybrid 
    BioGRID:36217 BioGRID:34685 TIM18    BioGRID  PubMed Dosage Rescue 
    BioGRID:36217 BioGRID:33595 TPK1    BioGRID  PubMed Biochemical Activity 
    BioGRID:36217 BioGRID:34099 TTI1    BioGRID  PubMed Synthetic Rescue 
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    General gene information

    Homology

    • Homologs of the TIP41 gene: The TIP41 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, and rice.

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    signal transduction IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Tip41p
    NP_015365.1
    • Protein that interacts physically and genetically with Tap42p, which regulates protein phosphatase 2A; component of the TOR (target of rapamycin) signaling pathway
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4

      Range
      647305..648375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184137.1 → NP_015365.1  Tip41p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q12199
      Conserved Domains (1) summary
      pfam04176
      Location:128 – 320
      Blast Score: 640
      TIP41; TIP41-like family
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006949.2 DAA11465.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q12199.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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