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HSP82 Hsp90 family chaperone HSP82 [ Saccharomyces cerevisiae S288c ]

Gene ID: 855836, updated on 12-Jul-2014
Gene symbol
HSP82
Gene description
Hsp90 family chaperone HSP82
Primary source
SGD:S000006161
Locus tag
YPL240C
Gene type
protein coding
RNA name
Hsp90 family chaperone HSP82
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HSP90
See HSP82 in MapViewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (96496..98625, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Iqg1p Neighboring gene Cin2p Neighboring gene Yar1p Neighboring gene Sui3p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity, coupled IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
unfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
'de novo' protein folding IDA
Inferred from Direct Assay
more info
PubMed 
'de novo' protein folding IMP
Inferred from Mutant Phenotype
more info
PubMed 
box C/D snoRNP assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of telomere maintenance via telomerase IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of telomere maintenance via telomerase IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of telomere maintenance via telomerase IPI
Inferred from Physical Interaction
more info
PubMed 
proteasome assembly IDA
Inferred from Direct Assay
more info
PubMed 
proteasome assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
proteasome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein folding IEA
Inferred from Electronic Annotation
more info
 
protein refolding IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein targeting to mitochondrion IPI
Inferred from Physical Interaction
more info
PubMed 
response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to stress IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
Names
Hsp90 family chaperone HSP82
NP_015084.1
  • Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 

    Range
    96496..98625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184054.1NP_015084.1  Hsp90 family chaperone HSP82 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_015084.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P02829
    Conserved Domains (3) summary
    cd00075
    Location:28160
    Blast Score: 121
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins
    PTZ00272
    Location:3709
    Blast Score: 2263
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
    pfam00183
    Location:183709
    Blast Score: 2091
    HSP90; Hsp90 protein