These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001098533.2 → NP_001092003.2 cyclin-dependent kinase 10 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (c) uses an alternate donor splice site at the first exon resulting in translation from a downstream start codon, and uses an alternate donor splice site in the 3' coding region, compared to variant a. The resulting isoform (c) has a shorter N-terminus and lacks a 6-aa segment near the C-terminus, compared to isoform a.
- Source sequence(s)
-
AK298386, BC017342, BM677573
- UniProtKB/TrEMBL
-
B7Z537
- UniProtKB/Swiss-Prot
-
Q15131
- Conserved Domains (1) summary
-
- cd07845
Location:1 – 262
Blast Score: 1321
- STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
-
NM_001160367.1 → NP_001153839.1 cyclin-dependent kinase 10 isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (d) uses an alternate donor splice site at the first exon resulting in translation from downstream start codon, compared to variant a. The resulting isoform (d) has a shorter N-terminus, compared to isoform a.
- Source sequence(s)
-
AC010538, AK298386, BC017342, BM677573
- UniProtKB/TrEMBL
-
B7Z537
- UniProtKB/Swiss-Prot
-
Q15131
- Related
- ENSP00000329957, OTTHUMP00000250390, ENST00000331006, OTTHUMT00000423068
- Conserved Domains (1) summary
-
- cd07845
Location:1 – 268
Blast Score: 1377
- STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
-
NM_052987.3 → NP_443713.2 cyclin-dependent kinase 10 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (b) uses an alternate donor splice site at the first exon resulting in translation from a downstream start codon, and uses an alternate acceptor splice site at the last exon, compared to variant a. The resulting isoform (b) has a shorter N-terminus and a shorter and distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
BC017342, BM677573, DB118903, L33264
- Consensus CDS
-
CCDS32514.2
- UniProtKB/Swiss-Prot
-
Q15131
- Related
- ENSP00000424415, OTTHUMP00000217847, ENST00000505473, OTTHUMT00000359827
- Conserved Domains (1) summary
-
- cl09925
Location:1 – 257
Blast Score: 1310
- PKc_like; Protein Kinases, catalytic domain
-
NM_052988.4 → NP_443714.3 cyclin-dependent kinase 10 isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (a) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
AK298386, BC017342, BM677573
- Consensus CDS
-
CCDS10984.2
- UniProtKB/TrEMBL
-
B7Z537
- UniProtKB/Swiss-Prot
-
Q15131
- Related
- ENSP00000338673, OTTHUMP00000175352, ENST00000353379, OTTHUMT00000269925
- Conserved Domains (2) summary
-
- PTZ00024
Location:43 – 336
Blast Score: 698
- PTZ00024; cyclin-dependent protein kinase; Provisional
- cd07845
Location:31 – 339
Blast Score: 1619
- STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
RNA
-
NR_027702.1 RNA Sequence
- Description
- Transcript Variant: This variant (e) lacks the second exon, compared to variant a. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant a, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK296631, AK298386, BC017342, BM677573
-
NR_027703.1 RNA Sequence
- Description
- Transcript Variant: Transcript Variant: This variant (f) lacks the second exon and uses an alternate acceptor splice site at the last exon, compared to variant a. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant a, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK298386, BC025301, BM677573
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000016.9 Reference GRCh37.p5 Primary Assembly
- Range
- 89753076..89762772
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000148.1 Alternate HuRef
- Range
- 75448350..75458046
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_003674.2: Suppressed sequence
- Description
- NM_003674.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.