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    HOL1 Hol1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855792, updated on 6-May-2012
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    Summary

    Gene symbol
    HOL1
    Gene description
    Hol1p
    Primary source
    SGD:S000005338
    Locus tag
    YNR055C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Location :
    chromosome: XIV
    Sequence :
    Chromosome: XIV; NC_001146.8 (728426..730186, complement)
    See HOL1 in MapViewer

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Esf2p Neighboring gene tRNA Neighboring gene Bio5p Neighboring gene Bio4p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Global functional map of the p23 molecular chaperone reveals an extensive cellular network. Echtenkamp FJ, et al. Mol Cell, 2011 Jul 22. PMID 21777812.
    2. The genetic landscape of a cell. Costanzo M, et al. Science, 2010 Jan 22. PMID 20093466.
    3. Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. Batisse J, et al. J Biol Chem, 2009 Dec 11. PMID 19840948.
    4. Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. Hasegawa Y, et al. RNA, 2008 Nov. PMID 18805955.
    5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310.

    See all (12) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:35881 BioGRID:35135 AMD1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34520 CAT5    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36005 CBC2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32737 CSG2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34464 CYT1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34046 CYT2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33335 DBF2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32446 EFT2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32564 EMI1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32569 EUG1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34435 EXO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:31157 FAR7    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34927 FIS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34442 GLO4    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34024 HAP4    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32665 HEK2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:35881 BioGRID:35111 IMD4    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:31528 LCB5    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34139 MEH1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34735 MNE1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:30926 MRC1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32172 MRPL1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33004 MTO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33129 NAB2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:35881 BioGRID:32052 NHP10    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34015 OAC1    BioGRID  PubMed PCA 
    BioGRID:35881 BioGRID:36903 PET122    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:35198 PEX12    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:35383 PFK2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33483 PHB2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32810 PHO88    BioGRID  PubMed PCA 
    BioGRID:35881 BioGRID:32953 POP4    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32294 PRP28    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36834 PTC2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33816 PTK2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36363 QCR2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:31012 RIM1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36679 RML2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34127 RPL14A    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36817 RPS24A    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34018 SBA1    BioGRID  PubMed Synthetic Lethality 
    BioGRID:35881 BioGRID:34916 SEC28    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:30971 SGF29    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33181 SGF73    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36863 SHO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:31016 SNT1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33938 SPE1    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:34352 SPE2    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:36241 SPE3    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:32454 SPT3    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:30951 STE50    BioGRID  PubMed Positive Genetic 
    BioGRID:35881 BioGRID:35325 SWP1    BioGRID  PubMed PCA 
    BioGRID:35881 BioGRID:32175 VBA4    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:37085 VMA9    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:31886 YDL180W    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:33611 YJL147C    BioGRID  PubMed Negative Genetic 
    BioGRID:35881 BioGRID:300661 YJR012C    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    alcohol transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    inorganic cation transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cation transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    organic alcohol transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
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    General protein information

    Names
    Hol1p
    NP_014453.1
    • Putative transporter in the major facilitator superfamily (DHA1 family) of multidrug resistance transporters; mutations in membrane-spanning domains permit cation and histidinol uptake
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8

      Range
      728426..730186, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183232.1 → NP_014453.1  Hol1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P53389
      Conserved Domains (1) summary
      cd06174
      Location:67 – 238
      Blast Score: 155
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006947.3 DAA10596.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53389.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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