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COQ2 4-hydroxybenzoate octaprenyltransferase [ Saccharomyces cerevisiae S288c ]

Gene ID: 855778, updated on 18-Feb-2015
Gene symbol
COQ2
Gene description
4-hydroxybenzoate octaprenyltransferase
Primary source
SGD:S000005324
Locus tag
YNR041C
Gene type
protein coding
RNA name
4-hydroxybenzoate octaprenyltransferase
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See COQ2 in MapViewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (700541..701659, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Zn(2+) transporter ZRG17 Neighboring gene hypothetical protein Neighboring gene diphosphomevalonate decarboxylase MVD1 Neighboring gene Aga1p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
4-hydroxybenzoate decaprenyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
4-hydroxybenzoate nonaprenyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
4-hydroxybenzoate octaprenyltransferase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
4-hydroxybenzoate octaprenyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
4-hydroxybenzoate octaprenyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
prenyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
ubiquinone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
ubiquinone biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
ubiquinone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
integral component of mitochondrial membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
Names
4-hydroxybenzoate octaprenyltransferase
NP_014439.3
  • Para hydroxybenzoate polyprenyl transferase; catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis; human COQ2, mutations in which are implicated in an increased risk of mutiple-system atrophy, is able to complement a yeast coq2 null mutant

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    700541..701659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183218.3NP_014439.3  4-hydroxybenzoate octaprenyltransferase [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_014439.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P32378
    Conserved Domains (1) summary
    cd13959
    Location:87363
    PT_UbiA_COQ2; 4-Hydroxybenzoate polyprenyltransferase