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    SCJ1 Scj1p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855254, updated on 8-Jan-2012
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    Summary

    Gene symbol
    SCJ1
    Gene description
    Scj1p
    Primary source
    SGD:S000004827
    Locus tag
    YMR214W
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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    Genomic context

    Sequence :
    Chromosome: XIII; NC_001145.3 (695350..696483)
    See SCJ1 in MapViewer

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Efr3p Neighboring gene Cef1p Neighboring gene Gas3p Neighboring gene Sky1p

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. Hoppins S, et al. J Cell Biol, 2011 Oct 17. PMID 21987634.
    2. Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin. Boettner DR, et al. Mol Biol Cell, 2011 Oct. PMID 21849475.
    3. Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Lee KK, et al. Mol Syst Biol, 2011 Jul 5. PMID 21734642.
    4. Secretory pathway genes assessed by high-throughput microscopy and synthetic genetic array analysis. Bircham PW, et al. Mol Biosyst, 2011 Sep. PMID 21731954.
    5. Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Scherrer T, et al. Genome Biol, 2011. PMID 21232131.

    See all (35) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:35392 BioGRID:31107 ACT1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36025 AIM44    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:35958 ALG5    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34405 ALG6    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34466 ALG8    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35861 ARC35    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:32864 ARL1    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:34596 BFR1    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:36534 BIG1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35876 BRE5    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36785 CAJ1    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35392 BioGRID:33405 CHO2    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:33419 CLC1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31772 CNE1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34084 CSE4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:33220 CWH41    BioGRID  PubMed Negative Genetic; Phenotypic Suppression; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:34131 DID4    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36699 ECM10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:32473 ERD1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31199 ERJ5    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35392 BioGRID:31759 ERP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:34635 ESA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35392 BioGRID:31270 FPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31717 GAB1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35487 GAS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33503 GCN5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:33226 GET1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:36828 GET2    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:36728 GIM4    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:35584 GIS2    BioGRID  PubMed Affinity Capture-RNA 
    BioGRID:35392 BioGRID:32388 GPI8    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33166 GUP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31115 HAC1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:35364 HSC82    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35392 BioGRID:35923 HSP82    BioGRID  PubMed Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35392 BioGRID:33874 ILM1    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:36513 IRE1    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:33682 JEM1    BioGRID  PubMed Dosage Rescue; Negative Genetic; Synthetic Growth Defect; Synthetic Lethality 
    BioGRID:35392 BioGRID:33726 KAR2    BioGRID  PubMed Affinity Capture-MS; Positive Genetic; Synthetic Lethality 
    BioGRID:35392 BioGRID:34719 KRE5    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36517 KSP1    BioGRID  PubMed Biochemical Activity 
    BioGRID:35392 BioGRID:34058 LHS1    BioGRID  PubMed Dosage Rescue; Positive Genetic 
    BioGRID:35392 BioGRID:31742 LTE1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35392 BioGRID:35024 MGA2    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34942 NEO1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35929 NSL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:33829 OPI3    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33755 OST1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34483 OST3    BioGRID  PubMed Negative Genetic; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:30941 PDI1    BioGRID  PubMed Negative Genetic; Synthetic Lethality 
    BioGRID:35392 BioGRID:33087 PMR1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31857 PPH22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:32915 PYC2    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35378 ROT1    BioGRID  PubMed Dosage Rescue; Synthetic Growth Defect 
    BioGRID:35392 BioGRID:32924 ROT2    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36451 RPS27B    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33953 SAC1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36296 SCD6    BioGRID  PubMed Two-hybrid 
    BioGRID:35392 BioGRID:35451 SCS7    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35013 SEC11    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33115 SEC27    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34916 SEC28    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:32217 SEC5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:34644 SEC63    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:35112 SPC2    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:32783 SPT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:35136 SRC1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35361 SSO2    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31518 SSP120    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:33873 STE24    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33224 STT3    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36987 SUS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:32376 SWA2    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31453 SWI6    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:32861 TOS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:36901 UBP3    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:33348 VMA21    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35392 BioGRID:33349 VOA1    BioGRID  PubMed Synthetic Growth Defect 
    BioGRID:35392 BioGRID:34133 VPS1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34091 VPS24    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:34152 VPS51    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:35392 BioGRID:33034 VRG4    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:31601 VRP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36729 WBP1    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:35759 YDJ1    BioGRID  PubMed Positive Genetic 
    BioGRID:35392 BioGRID:32638 YEL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:35392 BioGRID:33808 YJR054W    BioGRID  PubMed Negative Genetic 
    BioGRID:35392 BioGRID:36201 YME1    BioGRID  PubMed Positive Genetic 
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    General gene information

    Homology

    • Homologs of the SCJ1 gene: The SCJ1 gene is conserved in S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, and P.falciparum.

    Pathways from BioSystems

    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    chaperone binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    chaperone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    ER-associated protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein folding in endoplasmic reticulum IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    response to unfolded protein IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    endoplasmic reticulum lumen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Names
    Scj1p
    NP_013941.2
    • One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3

      Range
      695350..696483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182721.1 → NP_013941.2  Scj1p [Saccharomyces cerevisiae S288c]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P25303
      Conserved Domains (4) summary
      COG0484
      Location:21 – 377
      Blast Score: 715
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd06257
      Location:23 – 77
      Blast Score: 232
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
      cd10719
      Location:169 – 232
      Blast Score: 246
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
      cd10747
      Location:231 – 364
      Blast Score: 226
      DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic BK006946.2 DAA10113.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P25303.2 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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